Results 101 to 110 of about 1,678,198 (304)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Energy Procedia, 2018 Abstract To reach international climate goals, the research about energy consumption have to focus more on existing buildings. In the building sector, the increase of energy efficiency of buildings will not be sufficient to reduce the consumption of fossil resources significantly.
Rainer Schach +1 more
openaire +1 more source
Many-body dynamics and gap opening in interacting periodically driven systems
, 2017 We study the transient dynamics in a two-dimensional system of interacting Dirac fermions subject to a quenched drive with circularly polarized light. In the absence of interactions, the drive opens a gap at the Dirac point in the quasienergy spectrum ...
Kandelaki, Ervand, Rudner, Mark S.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Study The Use of Solar Energy for Heating Buildings in Baghdad City
Journal of Engineering and Sustainable Development, 2013 The research is devoted of study the possibility of using solar energy for the home heating systems by using the absorption refrigeration system and solar collector design has the ability to provide the heating system, solar thermal energy intake in ...
Ahmad Hassan Khuder
doaj
MICROWAVE RAPID HEATING SYSTEM USING CARBON HEATING TUBE
Proceedings 17th International Conference on Microwave and High Frequency Heating, 2019 We report a microwave heating system with a carbon heating tube (CHT) made by a 4-mm diameter quartz tube filled carbon particles and Ar gas at 1400 Pa. 2.45-GHz microwave at 200 W was introduced to a 300-dimameter metal cavity, in which 60-mm-long CHT was set at the central position.
Sameshima, Toshiyuki +7 more
openaire +3 more sources
Building energy performance characterisation based on dynamic analysis and co-heating test [PDF]
, 2014 A demonstration zero-carbon neighborhood is being raised in the city of Kortrijk, Belgium in the framework of the ECO-Life project within the CONCERTO initiative.
Himpe, Eline +2 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The Onset of Ion Heating During Magnetic Reconnection with a Strong Guide Field
, 2014 The onset of the acceleration of ions during magnetic reconnection is explored via particle-in-cell simulations in the limit of a strong ambient guide field that self-consistently and simultaneously follow the motions of protons and $\alpha$ particles ...
Drake, J. F., Swisdak, M.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source