Results 71 to 80 of about 1,678,198 (304)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
“Walczak’s Pipes” in the Greenhouse Heating System
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016 Diversified heating circuits inertia is particularly important by high variability of external conditions were the greenhouse is often overheated or large heat losses are noted. To meet these needs a new generation of heating pipes were used.
Kazimierz Rutkowski +5 more
doaj +1 more source
Thermal Comfort Analysis in Rooms Using Low Temperature Convective and Radiant Heating Terminals
Bulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2022 The concept of energy is closely related to the building sector and the systems used for heating, implicitly energy saving which is a current problem of both old and new buildings. In this paper a series of numerical simulations were made in Autodesk CFD
Vizitiu Ștefănica-Eliza +2 more
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Ionospheric disturbance overview [PDF]
, 1980 A program of research and exploratory development was undertaken to assess the potential impact of Satellite Power System operation on the ionosphere.
Rush, C. M.
core +1 more source
Resonances in a periodically driven bosonic system
, 2017 Periodically driven systems are a common topic in modern physics. In optical lattices specifically, driving is at the origin of many interesting phenomena.
Quelle, Anton, Smith, Cristiane Morais
core +2 more sources
Structural aspects of AlPO4-5 zeotypes synthesized by microwave-hydrothermal process. 1. Effect of heating time and microwave power [PDF]
, 2009 AlPO4-5 with AFI structure containing 12-membered rings was prepared using the aluminum isopropoxide precursor as a source of alumina and TEA as the structure directing agent via microwave technique.
Sakintuna, Billur +2 more
core +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source