Results 31 to 40 of about 714,229 (294)

Effects of geometry and orientation of food products on heating uniformity during radio frequency heating

, 2021
In radio frequency (RF) assisted heat treatment of food products, heating behavior depends on the composition and geometry of a product. In this study, the effect of salt added to a food simulant on its dielectric properties and penetration depth (dp ...
Erdogdu F., Lyng J. G., Bedane T. F., Marra F.   +3 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Field investigation of the impact of different terminal devices on thermal comfort and ventilation uniformity [PDF]

E3S Web of Conferences
Indoor thermal comfort and air quality in buildings significantly depend on heating, ventilation, and air conditioning (HVAC) system performance, particularly at the final stage through terminal units.
Wen Shikang, Chen Qingyan
doaj   +1 more source

Laser Heating Method for an Alkali Metal Atomic Cell with Heat Transfer Enhancement

Photonics, 2023
Alkali metal atomic cells are crucial components of atomic instruments, such as atomic magnetometers, atomic gyroscopes, and atomic clocks. A highly uniform and stable heating structure can ensure the stability of the alkali metal atom density. The vapor
Yang Li, Guoqing Zhou, Shencheng Tian, Xuejing Liu, Xiangmei Dong, Xiumin Gao   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Optimizing microwave heating with slotted metal tubes for cylindrical loads

Case Studies in Thermal Engineering
Cylindrical loads are commonly encountered in microwave heating and often suffer from uneven thermal distribution. Within certain radius and dielectric parameter ranges, cylindrical loads may exhibit central thermal focusing.
Yuanyuan Wu, Yuehao Ma, Junhao Su, Fengming Yang, Wencong Zhang, Chen Zhang, Yang Yang, Huacheng Zhu   +7 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Optimal design of heating system for electrical rapid heat cycle mold based on multi-objective optimization, multiple-attribute decision-making, and conformal design theory

Advances in Mechanical Engineering, 2018
To improve the heating efficiency and cavity surface temperature uniformity, an optimal design method was developed for the heating system in electrical rapid heat cycle molding mold. First, an electrical rapid heat cycle molding mold was simplified as a
Jiquan Li, Taidong Li, Xiang Peng, Feng Liu, Hangchao Zhou, Shaofei Jiang   +5 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source