Results 71 to 80 of about 1,466,687 (296)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Evaluation of Sewage Sludge for Incineration (Case study: Arak Wastewater Treatment Plant) [PDF]

Environmental Energy and Economic Research, 2017
Sewage sludge treatment has become a primary subject in wastewater treatment and energy production. This paper aims to study the feasibility of power generation by incineration from sewage sludge enriched with impurities like heavy metals.
AbdolReza Khalili, Shervin Jamshidi, Morteza Khalesidoust, Mohammadreza Vesali Naseh, Abbas Akbarzadeh, Mehran Mamaghani Nejad, Mohammad Mohebbi, Fariba Sameni   +7 more
doaj   +1 more source

Value of electric heat boilers and heat pumps for wind power integration

Wind Energy, 2007
AbstractThe paper analyses the economic value of using electric heat boilers and heat pumps as wind power integration measures relieving the link between the heat and power production in combined heat and power plants. Both measures have different technical and economic characteristics, making a comparison of the value of these measures relevant.
Meibom, Peter, Kiviluoma, Juha, Barth, Rüdiger, Brand, Heike, Weber, Christoph, Larsen, Helge, V.   +6 more
openaire   +6 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Parameter Kinetik Char Hasil Pirolisis Serbuk Kayu Mahoni (Switenia Macrophylla) Dengan Variasi Heating Rate Dan 1 Temperatur [PDF]

, 2015
The value of k (rate constant) is one of the important parameters in the equation speed of reaction (kinetics of reactions). This paper discusses the value of k (rate constan) at each heating rate (673 K / h and 873 K / h).
Hamidi, N. (Nurkholis), Majedi, F. (Farid), Wijayanti, W. (Widya)   +2 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Self-similar collapse with cooling and heating in an expanding universe

, 2003
We derive self-similar solutions including cooling and heating in an Einstein de-Sitter universe, and investigate the effects of cooling and heating on the gas density and temperature distributions.
Abadi, Arnaud, Bertschinger, Bertschinger, Brüggen, Brüggen, Brüggen, Churazov, Chuzhoy, Evrard, Fabian, Fillmore, Helsdon, Kaiser, Kaiser, Peebles, Peterson, Quilis, Reynolds, Ruszkowski, Shuji Uchida, Tadros, Tamura, Tatsuo Yoshida, Voigt, Zakamska   +25 more
core   +2 more sources

Electron Temperature of Ultracold Plasmas [PDF]

, 2004
We study the evolution of ultracold plasmas by measuring the electron temperature. Shortly after plasma formation, competition between heating and cooling mechanisms drives the electron temperature to a value within a narrow range regardless of the ...
C. D. Fertig, J. L. Roberts, J. I. H. Hutchinson, J. L. Spitzer, Jr., M. J. Lim, S. L. Rolston   +5 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source