Results 51 to 60 of about 86,221 (307)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Development of the structure of a cyberphysical control system for the process of tailored induction heating of a steel billet

Вестник Самарского государственного технического университета. Серия: Технические науки
The article is devoted to the development of the structure of a cyberphysical control system for the process of zone induction heating, widely used in modern industrial production during the heat treatment of metal products for various purposes.
S. А. Kolpashhikov, K. S. Peshkin
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Energy-efficient installations of multi-zone multi-frequency induction heating of steel billets for large deformation [PDF]

, 2020
This article discusses the basic construction principles of the device for multi-zone induction heating. The mathematical model of a cascade inverter is described.
Petrov, A. Y., Lopatin, I. E., Shalina, E. P., Lusgin, V. I., Alekseev, I. G., Fatkhullin, S. M.   +5 more
core   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Corrosion Behavior Characterization of the Nugget Zone in Copper/Brass Metals of Dissimilar Friction Stir Welded Lap Joints [PDF]

International Journal of Advanced Design and Manufacturing Technology, 2018
The electrochemical behavior of the weld nugget zone (WNZ) in copper-brass plates was studied in this paper. These plates were welded by the friction stir lap welding method in 1M NaCl solution at low heating input (450 rpm-25 mm/min ) and  high heating ...
kamran amini, Farhad Gharavi
doaj  

Modeling of Heat Flux in a Heating Furnace

Computation, 2023
Modern heating furnaces use combined modes of heating the charge. At high heating temperatures, more radiation heating is used; at lower temperatures, more convection heating is used. In large heating furnaces, such as pusher furnaces, it is necessary to
Augustín Varga, Ján Kizek, Miroslav Rimár, Marcel Fedák, Ivan Čorný, Ladislav Lukáč   +5 more
doaj   +1 more source

Heat Transfer in Evaporation Zone of Ammonia Aluminium Heat Pipes [PDF]

Research Bulletin of the National Technical University of Ukraine "Kyiv Politechnic Institute", 2017
Проблематика. В литературе отсутствуют обобщенные соотношения для расчета интенсивности теплообмена в зоне испарения аммиачных алюминиевых тепловых труб с канавчатой (конструкционной) капиллярной структурой, предназначенных для использования в системах обеспечения тепловых режимов космических аппаратов. Цель исследований.
Pis'mennyi, Eugene, Khairnasov, Sergii, Rassamakin, Boris   +2 more
openaire   +2 more sources

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Heating and cooling zone diagram of the continuous torsional refrigeration system.

, 2022
Heating and cooling zone diagram of the continuous torsional refrigeration system.
Haibo Zhao (198087), Kun Wu (286745)
core   +1 more source