Results 21 to 30 of about 1,472 (191)

Bronchoconstrictive properties of inhaled 8-epi-Pgf2alpha in healthy and heaves-susceptible horses [PDF]

, 2001
peer reviewedThe 8-epi-PGF2α is a marker of oxidative stress which is increased in lungs of asthmatic humans and heaves-susceptible horses. 8-Epi-PGF2α has also been demonstrated to be an in vitro and in vivo bronchoconstrictor in humans and rodents. We
Bureau, Fabrice, Tatiana Art, Nathalie Kirschvink, BUREAU, F., Kirschvink, Nathalie, LEKEUX, P., ART, T., Fabrice Bureau, Pierre Lekeux, Art, Tatiana, Lekeux, Pierre   +10 more
core   +1 more source

Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo. [PDF]

PLoS ONE, 2010
RATIONALE: Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors.
Patrick F Dillon, Robert Root-Bernstein, N Edward Robinson, William M Abraham, Catherine Berney   +4 more
doaj   +1 more source

Sealing Performance of the End Fitting of a Marine Unbonded Flexible Pipe under Pressure Penetration [PDF]

Journal of Applied and Computational Mechanics, 2020
The sealing performance of end fittings is very important for offshore oil and gas pipelines. To investigate the sealing behavior of a ring-shaped wedge seal, global and local numerical models of the ring–pipe interaction have been developed based on the
Liping Tang, Wei He, Xiaohua Zhu, Yunlai Zhou   +3 more
doaj   +1 more source

Bronchoalveolar Lavage Cytology Characteristics and Seasonal Changes in a Herd of Pastured Teaching Horses

Frontiers in Veterinary Science, 2019
Equine asthma syndrome (EAS) is a common problem that affects horses of any age. Severe EAS is reported to affect 10–20% of adult horses in the northern hemisphere, while mild/moderate EAS is reported to affect 60–100% of adult horses, depending on the ...
Kaori Uchiumi Davis, Kaori Uchiumi Davis, Mary Katherine Sheats, Mary Katherine Sheats   +3 more
doaj   +1 more source

Equine recurrent airway obstruction [PDF]

Macedonian Veterinary Review, 2014
Equine Recurrent Airway Obstruction (RAO), also known as heaves or broken wind, is one of the most common disease in middle-aged horses. Inflammation of the airway is inducted by organic dust exposure.
Artur Niedźwiedź
doaj   +1 more source

A comparison of nanoparticulate CpG immunotherapy with and without allergens in spontaneously equine asthma‐affected horses, an animal model

Immunity, Inflammation and Disease, 2018
Introduction New therapeutic strategies to modulate the immune response of human and equine allergic asthma are still under extensive investigation. Immunomodulating agents stimulating T‐regulatory cells offer new treatment options beyond conventional ...
John Klier, Sabine Geis, Jeanette Steuer, Katharina Geh, Sven Reese, Sebastian Fuchs, Ralf S. Mueller, Gerhard Winter, Heidrun Gehlen   +8 more
doaj   +1 more source

Immunomodulatory asthma therapy in the equine animal model: A dose‐response study and evaluation of a long‐term effect

Immunity, Inflammation and Disease, 2019
Introduction Equine asthma represents a naturally occurring animal model for human allergic neutrophilic asthma. Inhalative nanoparticle‐bound cytosine‐phosphate‐guanosine (CpG‐GNP) immunotherapy, independent of specific allergens, has already shown ...
John Klier, Carolin Bartl, Sabine Geuder, Katharina J. Geh, Sven Reese, Lutz S. Goehring, Gerhard Winter, Heidrun Gehlen   +7 more
doaj   +1 more source

An approach to determine brittle upper crustal thinning: Insights into crustal extension discrepancy in the central part of Qiongdongnan Basin

Frontiers in Earth Science, 2023
Summing fault heaves is the most commonly used method to evaluate upper crustal thinning. However, since fault deformation width (W) is often assumed as a constant in the range of 75–150 km, the stretching factor estimated from fault geometry (βf ...
Chao He, Chao He, Zhongxian Zhao, Eun Young Lee, Yulong Xue, Yulong Xue   +5 more
doaj   +1 more source

On the Responses of Braced Diaphragm Wall Supporting Deep Excavation Subjected to Asymmetric Surcharge Loads

Advances in Civil Engineering, 2023
As cities grow, so does the need for housing and transportation infrastructure, necessitating deep excavations. Near the deep excavation, especially in the urban centers, there are existing structures whose loads are often different, resulting in ...
Recep Akan
doaj   +1 more source

Some Genetic and Environmental Effects on Equine Asthma in Polish Konik Horses

Animals, 2021
Current knowledge of the genetic and environmental backgrounds of equine asthma seems to be insufficient, especially for primitive horse breeds. The main objectives of this study were to estimate the effects of sex, birth period, stud, parentage line and
Alicja Borowska, Daria Wolska, Artur Niedzwiedz, Hieronim Borowicz, Zbigniew Jaworski, Marta Siemieniuch, Tomasz Szwaczkowski   +6 more
doaj   +1 more source