Results 171 to 180 of about 45,296 (313)

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Physics of high-energy heavy-ion collisions

, 2006
This a review of the present status of heavy-ion collisions at intermediate energies. The main goal of heavy-ion physics in this energy regime is to shed some light on the nuclear equation of state (EOS), hence we present the basic concept of the EOS in ...
Greiner, Walter, Stöcker, Horst, Peilert, Georg   +2 more
core  

Boosting the Photoluminescence of Au@Cu12 Nanoclusters via Strategic Fluorine‐Atom Ligand‐Shell Engineering

Journal of the Chinese Chemical Society, EarlyView.
The photophysical performance of gold‐doped copper‐rich nanoclusters can be tuned by surface functionalization. Subtle ligand modification enhances intermolecular interactions, thereby reducing nonradiative decay and markedly improving photoluminescence. Comparative photographs and quantum yield values (Φ = 55% vs.
Navya Indla, Wei‐Jung Yen, Yu‐Rong Ni, Jian‐Hong Liao, Xiaoping Wang, Michael N. Pillay, C. W. Liu   +6 more
wiley   +1 more source

Heavy-flavour and quarkonium production in the LHC era: from proton-proton to heavy-ion collisions. [PDF]

Eur Phys J C Part Fields, 2016
Andronic A, Arleo F, Arnaldi R, Beraudo A, Bruna E, Caffarri D, Del Valle ZC, Contreras JG, Dahms T, Dainese A, Djordjevic M, Ferreiro EG, Fujii H, Gossiaux PB, de Cassagnac RG, Hadjidakis C, He M, van Hees H, Horowitz WA, Kolevatov R, Kopeliovich BZ, Lansberg JP, Lombardo MP, Lourenço C, Martinez-Garcia G, Massacrier L, Mironov C, Mischke A, Nahrgang M, Nguyen M, Nystrand J, Peigné S, Porteboeuf-Houssais S, Potashnikova IK, Rakotozafindrabe A, Rapp R, Robbe P, Rosati M, Rosnet P, Satz H, Schicker R, Schienbein I, Schmidt I, Scomparin E, Sharma R, Stachel J, Stocco D, Strickland M, Tieulent R, Trzeciak BA, Uphoff J, Vitev I, Vogt R, Watanabe K, Woehri H, Zhuang P.   +55 more
europepmc   +1 more source

Large-scale two-particle correlation sructures in Au-Au collisions at center of mass energy = 130 GeV

, 2004
textThe first measurement of surviving correlation structure in the final-state charged hadron distribution produced in the collisions of gold nuclei at √ sNN = 130 GeV is presented.
Ishihara, Aya, 1974-
core  

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Recent advances in Joule‐heating synthesis of functional nanomaterials for photo and electrocatalysis

PhotoMat, EarlyView.
This paper presents a comprehensive overview of recent advancements in Joule‐heating synthesis of photo and electrocatalysts, emphasizing its benefits and applications. The objective is to offer an effective strategy for enhancing the diversity and performance of catalytic materials.
Jiaqi Li, Laiyu Luo, Siyu Wang, Haojie Song, Baojiang Jiang   +4 more
wiley   +1 more source

Production of W± bosons in the semi-muonic channel at forward rapidity in ALICE

, 2013
Heavy-ion collisions are the unique tool available to investigate strongly interacting matter at high energy density where the formation of a new phase of matter −the quark gluon plasma is expected. The ALICE Muon Spectrometer is specifically designed to
Senosi, Kgotlaesele Johnson
core