Results 71 to 80 of about 5,223 (263)
A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg +16 more
wiley +1 more source
Emissivity and conductivity of parton-hadron matter
We investigate the properties of the QCD matter across the deconfinement phase transition. In the scope of the parton-hadron string dynamics (PHSD) transport approach, we study the strongly interacting matter in equilibrium as well as the out-of ...
Linnyk O. +4 more
doaj +1 more source
Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi +5 more
wiley +1 more source
This book contains information on the following topics: collective variables and dissipation; energy dissipation in nucleus-nucleus collision around 40 MeV per nucleon; spectral fluctuations and chaotic motion; dynamics of the relativistic heavy ion collisions; skyrmions, dense matter and nuclear forces; angular momentum dynamics in damped nuclear ...
openaire +1 more source
Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley +1 more source
We systematically investigate the pion transverse momentum spectrum, elliptic flow, and Hanbury-Brown-Twiss (HBT) interferometry in the granular source model for the heavy ion collisions of Au-Au at sNN=200 GeV and Pb-Pb at sNN=2.76 TeV with different ...
Jing Yang, Yan-Yu Ren, Wei-Ning Zhang
doaj +1 more source
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
Overview of recent CMS results [PDF]
Recent results from the CMS Collaboration are presented. These measurements include a full physics program using ultraperipheral collisions such as photon-photon and photon-ion interactions, small collision systems including proton-proton and proton-lead
Baty Austin
doaj +1 more source
UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma +14 more
wiley +1 more source
Gold Clusters With Open‐Shell Ligands: Superatom Mediated Magnetic Interaction
Open‐shell verdazyl radicals were covalently integrated with atomically precise Ir‐doped Au12 (Ir@Au12) superatoms. The resulting radical–superatom hybrids exhibit photoinduced electron transfer, spin delocalization onto the metal‐cluster core, and weak ferromagnetic communication between radicals mediated by the superatomic electronic structure ...
Katsuya Mutoh +7 more
wiley +2 more sources

