Results 41 to 50 of about 117,235 (311)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Probing nucleon-nucleon correlations in heavy-ion transfer reactions

EPJ Web of Conferences, 2016
The γ-particle coincident measurements, performed by coupling of the PRISMA spectrometer to the large γ arrays (CLARA and AGATA), demonstrate a strong interplay between single-particle and collective degrees of freedom that is pertinent to the reaction ...
Szilner S.
doaj   +1 more source

Modeling Double Charge Exchange processes occurring in Heavy Ion Reactions [PDF]

EPJ Web of Conferences
Heavy ion induced double charge exchange reactions are treated as an incoherent sequence of two reactions driven by the exchange of charged mesons (double single charge exchange, DSCE). The process is described within a fully quantum mechanical distorted
Bellone Jessica Ilaria, Colonna Maria, Gambacurta Danilo, Lenske Horst   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A fourier transform-ion cyclotron resonance study of steric effects on proton transfer reactions of polyalkyl benzenes

, 1991
Büker H-H, Grützmacher H-F. A fourier transform-ion cyclotron resonance study of steric effects on proton transfer reactions of polyalkyl benzenes. International Journal of Mass Spectrometry and Ion Processes.
Büker, Heinz-Hermann, Hans-Friedrich Grützmacher, Heinz-Hermann Büker, Grützmacher, Hans-Friedrich   +3 more
core   +1 more source

Surrogate Reactions at Heavy-Ion Storage Rings: The NECTAR Project

, 2023
International audienceSurrogate Reactions at Heavy-Ion Storage Rings: The NECTAR ...
Beatriz Jurado, Jurado, Beatriz
core   +1 more source

Flexible algorithms for background suppression in heavy ion induced nuclear reactions

Eurasian Journal of Physics and Functional Materials, 2022
A new algorithm for the analog spectrometer of the DGFRS-2 setup installed at DC-280 cyclotron is presented. The main goal of application of this algorithm is to search an optimal time correlation recoilalpha parameter directly during the acquisition C++
D. Ibadullayev, Yu. S. Tsyganov, A. N. Polyakov, A. A. Voinov, V. G. Subbotin, M. V. Shumeiko, L. Schlattauer   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Effects of reaction ion kinetic energy on both endothermic and exothermic ion/molecule reactions in a quadrupole ion trap mass spectrometer

, 2011
The effects of kinetic energy on the outcomes of exothermic and endothermic ion/molecule reactions in a quadrupole ion trap mass spectrometer are examined.
Wu, H. F. ; 吳慧芬; Brodbelt, J. S.
core   +1 more source

Isospin Diffusion in Heavy Ion Reactions

, 2003
Using symmetric 112Sn+112Sn, 124Sn+124Sn collisions as references, we probe isospin diffusion in peripheral asymmetric 112Sn+124Sn, 124Sn+112Sn systems at incident energy of E/A=50 MeV. Isoscaling analyses imply that the quasi-projectile and quasi-target in these collisions do not achieve isospin equilibrium, permitting an assessment of the isospin ...
Tsang, M., Liu, T. X., Shi, L., Danielewicz, P., Gelbke, C. K., Liu, X. D., Lynch, W. G., Tan, W. P., Verde, G., Wagner, A., Xu, H. S., Friedman, W. A., Beaulieu, L., Davin, B., Souza, R. T., Larochelle, Y., Lefort, T., Yanez, R., Viola Jr., V. E., Charity, R. J., Sobotka, L. G.   +20 more
openaire   +3 more sources