Results 61 to 70 of about 233,260 (285)
A New Family of Modified Slash Distributions with Applications
Mathematics, 2023 This article presents a new family of symmetric heavy-tailed distributions. This model is based on the ratio of two independent random variables; one with a normal distribution in the numerator and another with a Birnbaum–Saunders distribution in the ...
Jimmy Reyes, Yuri A. Iriarte
doaj +1 more source
bioRxiv, 2018 Variance in reproductive success is a major determinant of the degree of genetic drift in a population. While many plants and animals exhibit high variance in their number of progeny, far less is known about these distributions for microorganisms.
E. Wright, Kalin H. Vetsigian
semanticscholar +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Method for Confidence Intervals of High Quantiles
Entropy, 2021 The high quantile estimation of heavy tailed distributions has many important applications. There are theoretical difficulties in studying heavy tailed distributions since they often have infinite moments.
Mei Ling Huang, Xiang Raney-Yan
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Metapopulation models imply non-Poissonian statistics of interevent times
Physical Review Research, 2022 Interevent times in temporal contact data from humans and animals typically obey heavy-tailed distributions, which impacts contagion and other dynamical processes on networks.
Elohim Fonseca dos Reis, Naoki Masuda
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PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Sensors, 2019 In maneuvering target tracking applications, the performance of the traditional interacting multiple model (IMM) filter deteriorates seriously under heavy-tailed measurement noises which are induced by outliers.
Dong Li, Jie Sun
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On the interference arising from random spatial fields of interferers utilizing multiple subcarriers
EURASIP Journal on Wireless Communications and Networking, 2022 Effective symbol detection, channel estimation and decoding of channel codes require an accurate characterization of the noise probability distribution.
Ce Zheng +4 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source