Results 51 to 60 of about 121,317 (315)

Integrated experiments for heavy ion fusion

open access: yesLaser and Particle Beams, 2003
We describe the next set of experiments proposed in the U.S. Heavy Ion Fusion Virtual National Laboratory, the so-called Integrated Beam Experiment (IBX). The purpose of IBX is to investigate in an integrated manner the processes and manipulations necessary for a heavy ion fusion induction accelerator. The IBX experiment will demonstrate injection,
Barnard, J.J.   +18 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Inclusive J/ψ production at mid-rapidity in pp collisions at s $$ \sqrt{s} $$ = 5.02 TeV

open access: yesJournal of High Energy Physics, 2019
Inclusive J/ψ production is studied in minimum-bias proton-proton collisions at a centre-of-mass energy of s $$ \sqrt{s} $$ = 5.02 TeV by ALICE at the CERN LHC. The measurement is performed at mid-rapidity (|y| < 0.9) in the dielectron decay channel down
The ALICE collaboration   +1025 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Heavy ion collision experiments at NICA [PDF]

open access: yesProceedings of The 39th International Conference on High Energy Physics — PoS(ICHEP2018), 2019
The NICA (Nuclotron-based Ion Collider fAcility) project is under realization at the Joint Institute for Nuclear Research (JINR, Dubna). The main goal of the project is an experimental study of hot and dense strongly interacting 
matter in heavy ion (up to Au) collisions at center-of-mass energies up to 11 GeV per nucleon.
Vladimir Kekelidze   +5 more
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Laser-Cooled Ion Beams and Strongly Coupled Plasmas for Precision Experiments [PDF]

open access: yes, 2008
The first part of this thesis summarizes the results of laser-cooling of relativistic C3+ ion beams at the ESR/GSI. It is shown that laser cooling at high beam energies is feasible and that momentum spreads much smaller than those observed for electron ...
Bussmann, Michael
core  

Nonequilibrium models of relativistic heavy-ion collisions

open access: yes, 2005
To be published in J. Phys. G - Proceedings of SQM 2004 : We review the results from the various hydrodynamical and transport models on the collective flow observables from AGS to RHIC energies.
S Soff   +13 more
core   +1 more source

Rivet and the analysis preservation in heavy-ion collisions experiments

open access: yes, 2023
The comparison of experimental data and theoretical predictions is important for our understanding of the mechanisms for interactions and particle production in hadron collisions, both at the Large Hadron Collider and at the Relativistic Heavy-Ion ...
da Silva, Antonio Carlos Oliveira
core   +1 more source

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