Results 111 to 120 of about 2,084,774 (316)

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

Effects of pores structure of MgO-templated combined with KOH active porous carbon on its supported Pt catalysts for enhanced electrocatalytic reactions

Green Chemical Engineering
Pore structures in carbon materials have been referred to regulate the properties of carbon, which are meaningful for improving electro-catalytic performance.
Yang Sun, Jianfeng Wang, Siyuan Sun, Haojia Zhong, Kexin Wei, Hongchen Liu, Qiang Wei, Yongfeng Li, Fan Yang   +8 more
doaj   +1 more source

Shale oil technical advisory committee, minutes of the second special meeting

, 2022
Includes charts.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical Advisory Committee was formed by Socony Mobil, ESSO Research and ...

core  

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Hydrodesulfurization of Heavy Oil

Journal of the Fuel Society of Japan, 1966
From the viewpoint of pollution control, desulfurization of heavy oil has become important problem to be solved urgently. In this country studies are being little carried out in this field, however, in foreign countries its industrialization is being taken into consideration.This paper, describes catalytic hydrodesulfurization of atmospheric/reduced ...
openaire   +2 more sources

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

Advances in Architectural Design, Propulsion Mechanisms, and Applications of Asymmetric Nanomotors

Nanomaterials
Asymmetric nanomotors are a class of self-propelled nanoparticles that exhibit asymmetries in shape, composition, or surface properties. Their unique asymmetry, combined with nanoscale dimensions, endows them with significant potential in environmental ...
Yanming Chen, Meijie Jia, Haihan Fan, Jiayi Duan, Jianye Fu   +4 more
doaj   +1 more source

Demonstration of yield and operability retorting 3/4 to 1 1/2 inch oil shale at 500 lbs/(hr) (ft2) in retort no. 2

, 2022
Technical memorandum no. 66-2.Includes charts.These technical memoranda pertain to work performed at Anvil Points.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated ...

core  

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

Advanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai, Shuhong Wang, Chenguang Ding, Xenia Kostoulias, Anton P. Le Brun, Hsien‐Yi Hsu, Jhih‐Hang Jiang, Yajun Wang, Richard A. Strugnell, Anton Y. Peleg, Hsin‐Hui Shen   +10 more
wiley   +1 more source

Nine-Lump Kinetic Study of Catalytic Pyrolysis of Gas Oils Derived from Canadian Synthetic Crude Oil

International Journal of Chemical Engineering, 2016
Catalytic pyrolysis of gas oils derived from Canadian synthetic crude oil on a kind of zeolite catalyst was conducted in a confined fluidized bed reactor for the production of light olefins.
Rui Zhang, Li Li, Zhichang Liu, Xianghai Meng   +3 more
doaj   +1 more source