Results 31 to 40 of about 968,303 (311)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Quantification and optimization of platinum–molybdenum carbide interfacial sites to enhance low-temperature water-gas shift reaction

Nature Communications
Pt/α-MoC1-x catalysts exhibit exceptional activity in low-temperature water-gas shift reactions. However, quantitatively identifying and fine-tuning the active sites has remained a significant challenge.
Ruiying Li, Jingyuan Shang, Fei Wang, Qing Lu, Hao Yan, Yongxiao Tuo, Yibin Liu, Xiang Feng, Xiaobo Chen, De Chen, Chaohe Yang   +10 more
doaj   +1 more source

Hydrogenolysis of Glycerol to Propylene Glycol: Energy, Tech-Economic, and Environmental Studies

Frontiers in Chemistry, 2022
Hydrogenolysis of glycerol to propylene glycol represents one of the most promising technologies for biomass conversion to chemicals. However, conventional hydrogenolysis processes are often carried out under harsh H2 pressures and temperatures, leading ...
Puhua Sun, Wenxiang Zhang, Xiao Yu, Jie Zhang, Ningkun Xu, Zhichao Zhang, Mengyuan Liu, Dongpei Zhang, Guangyu Zhang, Ziyuan Liu, Chaohe Yang, Wenjuan Yan, Xin Jin   +12 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Uniformly dispersed bismuth metal nano catalyst modified carbon cloth electrode for iron-chromium flow battery

Nano Research Energy
Due to the advantages of low cost and good stability, iron-chromium flow batteries (ICRFBs) have been widely used in energy storage development. However, issues such as poor Cr3+/Cr2+ activity still need to be addressed urgently.
Yinping Liu, Chao Guo, Guangfu Wu, Wenjie Lv, Ruichen Zhou, Wei Qiu, Yang Zhou, Quan Xu, Chunming Xu, Yingchun Niu   +9 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Catalytic oxidation upcycling of polyethylene terephthalate to commodity carboxylic acids

Nature Communications
Catalytic upcycling of polyethylene terephthalate (PET) into high-value oxygenated products is a fascinating process, yet it remains challenging. Here, we present a one-step tandem strategy to realize the thermal catalytic oxidation upcycling of PET to ...
Qinghai Chen, Hao Yan, Kai Zhao, Shuai Wang, Dongrui Zhang, Yaqian Li, Rong Fan, Jie Li, Xiaobo Chen, Xin Zhou, Yibin Liu, Xiang Feng, De Chen, Chaohe Yang   +13 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Efficient Fe based catalyst with nitrogen doped carbon material modification for propane non-oxidative dehydrogenation

Carbon Resources Conversion, 2020
Nitrogen doped carbon species (NC) was introduced into Fe based catalyst and applied into propane non-oxidative dehydrogenation. With characterizations of XRD, TEM and XPS, it was deduced that the NC modification induces the electrons transferred from NC
Yuming Li, Qiyang Zhang, Xue Yu, Guiling Jiang, Yajun Wang, Guiyuan Jiang, Zhen Zhao, Chunming Xu   +7 more
doaj   +1 more source

Aplikasi Peminjaman Alat-Alat Berat Di PT. Truba Jaya Engginering [PDF]

, 2018
PT. Truba Jaya Engginerimg is a state-owned company engaged in natural resources such as the construction of power plants, oil and gas plants, cement, pulp and paper factories, mining and civil works processing plants.
Sitorus, Benny Mauli
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