Results 21 to 30 of about 1,669 (187)
ABSTRACT Dry eye syndrome (DES) happens as a result of inadequate tear secretion or excessive evaporation, which leads to ocular surface irritation and damage. A major therapeutic challenge is maintaining effective drug concentrations, as topical formulations are rapidly cleared by blinking and tear turnover.
Masoumeh Alsadat Hosseini +6 more
wiley +1 more source
Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian +11 more
wiley +1 more source
ABSTRACT Climate change, with its links to an intensified water cycle, heavier rainfall, and potentially higher flood peaks, raises concerns about the adequacy of current flood risk management. The devastating July 2021 floods in western Europe underscored these concerns, highlighting the need for transboundary cooperation and shared expertise in ...
Elena Macdonald +8 more
wiley +1 more source
Muchas especies de carnívoros conforman letrinas al acumular sus heces en sitios específicos. Estas sirven para marcar su territorio y advertir a otros individuos sobre su presencia, como una estrategia para evitar competencia directa por el área y sus ...
Juan D. Sánchez-Londoño
doaj +1 more source
Urbanization of seed dispersal networks
Abstract Rapid urban expansion is affecting the composition of wild communities and creating novel ecosystems worldwide. Seed dispersal is key for ecosystem persistence, particularly in fragmented landscapes. However, generalizations regarding the impacts of urbanization are still difficult due to the lack of studies encompassing the urban matrix.
Sara Beatriz Mendes +6 more
wiley +1 more source
La cuantificación indirecta de la carga ganadera localizada en un determinado lugar dentro de un potrero puede ser una herramienta útil para estudiar los patrones de distribución espacial y temporal del ganado. En este trabajo nos propusimos identificar
Axel R. von Müller +3 more
doaj +1 more source
Bridge Clogging in Belgium and Germany During the 2021 Floods
Abstract During summer of 2021, devastating river floods occurred in Western Europe as a result of extreme rainfall. At numerous bridges, debris accumulations were observed, exacerbating flooding upstream by impeding waterflow and sometimes contributing to bridge failure.
Daan W. Poppema +6 more
wiley +1 more source
Introducción. Belminus ferroae es un triatomino de comportamiento entomófago, sin embargo, puede alimentarse de vertebrados ocasionalmente. No se ha demostrado infección natural por Trypanosoma cruzi en esta especie, como tampoco la metaciclogénesis del ...
Maritza Alarcón +5 more
doaj +1 more source
ABSTRACT Research on business models for sustainability (BMfS) has primarily focused on the conceptual aspects and sustainability potential of BMfS rather than their actual impact. There is a need to understand whether BMfS have less environmental impact on society than conventional business models and in what context and conditions they can reduce ...
Emma Johnson, Oksana Mont
wiley +1 more source
Dada la importancia de la criptosporidiosis en salud pública, se desarrolló un estudio en el Valle de Chiquinquirá, Boyacá- Colombia, analizando la proporción de animales y de fincas positivas y las variables alojamiento, origen del agua, edad, tamaño de
Juan Montaño, Catalina Avendaño
doaj

