Examining the safe-haven and hedge capabilities of gold and cryptocurrencies: A GARCH and regression quantiles approach in geopolitical and market extremes. [PDF]
Ben Ameur H, Jamaani F, N Abu Alfoul M.
europepmc +1 more source
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Measuring individual differences in the speed of attention using the distractor intrusion task. [PDF]
Zivony A, von Bastian CC, Pye R.
europepmc +1 more source
PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang +13 more
wiley +1 more source
Changes in the network structure of energy markets and financial markets under the different shocks of the Russia-Ukraine conflict and COVID-19. [PDF]
Li F, Tong M, Guan S.
europepmc +1 more source
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui +18 more
wiley +1 more source
Novel Quantification of Eggshell Surfaces in <i>Dromaius novaehollandiae</i> With Implications for the Fossil Eggshells of Oviraptorosauria (Dinosauria). [PDF]
Hedge J, Bender E, Zanno LE.
europepmc +1 more source
Recent advances in research on hedge fund activism: Value creation and identification
Alon Brav, Wei Jiang, Hyunseob Kim
semanticscholar +1 more source
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing +10 more
wiley +1 more source
Exploring Hedging Devices in Scientific Research Papers: A Content Analysis Study of the 'Medical Journal of the Islamic Republic of Iran'. [PDF]
Hamidi H, Najafi Sarem S, Lotfi AH.
europepmc +1 more source

