Results 81 to 90 of about 11,937 (268)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Global Derivatives Market

open access: yesSEEU Review, 2017
Globalization of financial markets led to the enormous growth of volume and diversification of financial transactions. Financial derivatives were the basic elements of this growth.
Stankovska Aleksandra
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Evolution d'une unité agro-sylvo-pastorale de moyenne montagne sur les communes de Sost et d'Esbareich (Barousse-Hautes Pyrénées) de 1833 à 1933. Modalités-Causes-Conséquences

open access: yesPirineos: Revista de Ecología de Montaña, 1997
[fr] L'étude de formations forestières montagnardes de la vallée de la Barousse (Pyrénées Centrales), au sein desquelles on été choisies plus particulièrement trois stations, a conduit à prendre en compte l'ensemble du territoire où elles se situent ...
J. Mazars
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Portfolio Management in Times of Elevated Risk. Safe-Haven and Hedge Assets in CAPM Setting

open access: yesFinanse i Prawo Finansowe
The purpose of the article. The purpose of the article is to present the safe-haven concept according to the latest academic literature and distinguish it from the hedge and diversifier terms that are sometimes used interchangeably by researchers and ...
Ewa Feder-Sempach
doaj   +1 more source

¿Reforzador o atenuador? 'Evidentemente' como adverbio evidencial en el discurso académico escrito [PDF]

open access: yesSintagma, 2008
Working on an applying corpus consisting of lectures and scientific articles belonging to hard sciences, social sciences and humanities, in the present article my aim is to identify and describe within the frame of Argumentative Semantics the ...
Andrea Estrada
doaj  

Evaluation of growth and flowering of cultivars derived from the rugosa (Rosa rugosa Thunb.) growing in the national collection of rose cultivars in the Polish Academy of Sciences Botanical Garden in Powsin. Part I. The historical cultivars

open access: yesActa Agrobotanica, 2012
In the years 2000-2011, observations were made of shrubs of the cultivars derived from the Rugosa (R. rugosa Thunb.) gathered in the Collection of Rose Cultivars of the Polish Academy of Sciences (PAS) Botanical Garden – Center for Biological Diversity ...
Marta J. Monder
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

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