Results 101 to 110 of about 926,017 (305)
A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance
Advanced Science, EarlyView.Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng +12 more
wiley +1 more source
Performance measurement of hedge funds managers [PDF]
This article summarizes criteria used to identify investment talent in (especially hedge fund) managers and stresses the importance of identifying criteria that are not primarily soft but whose validity can be back tested.Performance; Determinants of ...
Cristian TIU +3 more
core
Advanced Science, EarlyView.Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon +6 more
wiley +1 more source
The popular perception is that hedge funds follow a reasonably well defined market-neutral investment style. While this long-short investment strategy may have characterized the first hedge funds, today hedge funds are a reasonably heterogeneous group ...
Stephen J. Brown, William N. Goetzmann
core
Advanced Science, EarlyView.Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley +1 more source
Further Evidence on Hedge Funds Performance. [PDF]
In this analysis we identify dynamic hedge fund strategies quantitatively pursuing a Principal Component Analysis following Fung and Hsieh (1997). We extract five dominant hedge fund strategies each representing similar investment styles and analyse the ...
Madsen, Peter Brink +2 more
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Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-BiałejThe review article is dedicated to the issues of financial instruments in the context of the new regulation of the Minister of Finance on the recognition and valuation methods, as well as the disclosure and presentation of financial instruments.
Anna Biśta
doaj +1 more source
THE EFFECT OF DERIVATIVE FINANCIAL INSTRUMENTS ON BANK RISKS, RELEVANCE AND FAITHFUL REPRESENTATION: EVIDENCE FROM BANKS IN HUNGARY [PDF]
Annals of the University of Oradea: Economic Science, 2014 In a continuously changing business environment accounting data have to provide useful information in order to achieve relevant and faithful representation in financial statements.
Toth Kornel, , ,
doaj
Simultaneous Hedging of Regulatory and Accounting CVA [PDF]
, 2016 As a consequence of the recent financial crisis, Basel III introduced a new capital charge, the CVA risk charge to cover the risk of future CVA fluctuations (CVA volatility). Although Basel III allows for hedging the CVA risk charge, mismatches between the regulatory (Basel III) and accounting (IFRS) rules lead to the fact that hedging the CVA risk ...
openaire +1 more source
Advanced Science, EarlyView.A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang +12 more
wiley +1 more source