Results 201 to 210 of about 1,860 (264)

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

Sonoselective Transfection of Glioma Endothelium

Advanced Science, EarlyView.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski, Catherine M. Gorick, Victoria R. Breza, Jackson Tirrell, Krishan Perumal, Katherine M. Nowak, Ji Song, Natasha D. Sheybani, Richard J. Price   +8 more
wiley   +1 more source

Coordinated optimization of reserve fund scale and emergency resource allocation for power utilities under multi-type large-scale blackout risks. [PDF]

PLoS One
Gu Y, Zhang Z, Zhang L.
europepmc   +1 more source

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source

Comparative Configurational Process Analysis: A New Set-Theoretic Technique for Longitudinal Case Analysis. [PDF]

Organ Res Methods
Rupietta C, Meuer J.
europepmc   +1 more source

How to address solar geoengineering's transparency problem. [PDF]

Proc Natl Acad Sci U S A
Talati S, Buck HJ, Kravitz B.
europepmc   +1 more source

Health in the age of asset manager capitalism. [PDF]

Health Promot Int
Wood B, McLean A, Sacks G.
europepmc   +1 more source

Constructing stability: optimal learning in noisy ecological niches. [PDF]

Proc Biol Sci
Lee ED, Flack JC, Krakauer DC, Krakauer DC.   +3 more
europepmc   +1 more source

A global dataset of experimental agricultural management on soil carbon accrual, its synergies and trade-offs. [PDF]

Sci Data
Sánchez-Moreno S, Ros MBH, Walder F, Peixoto L, Gómez-Gallego T, Jeanbille M, Juhanson J, Feiza V, Aponte C, Pulido-Moncada M, Parasotas I, Kochiieru M, Amaleviciute-Volunge K, Dammie N, van der Heijden MGA, Ramos JL, Feizene D, Philippot L, Munkholm L, Velthof GL, Petersen SO, Hallin S, Goberna M.   +22 more
europepmc   +1 more source