Results 41 to 50 of about 105,263 (297)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Investment Management Strategy in Financial Markets
ECONOMICS, 2018 The subject matter of this research is investment management and its forms practiced in developed financial markets. The goal of this research is to elaborate on the strategies and characteristics of investment companies, hedge funds, venture capital ...
Vunjak Nenad +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
THE EFFECT OF HEDGE FUNDS ON THE TRANSFORMATION OF THE WORLD ECONOMIC RELATIONS
Мир новой экономики, 2018 Today, hedge funds are some of the most effective financial players able to show high earnings despite the crisis in the global economy and international financial markets. However, their work iscontroversial: often the high yield means the specific ways
FEODOR ALEKSANDROVICH Smirnov
doaj
International Journal of Financial Studies, 2017 In this study, we attempt to identify the asset which has the best hedging characteristics against inflation. We study stock, bond, commodity, real estate and oil indexes. We also study these indexes tracking exchange traded funds (ETFs) to determine the
Stoyu I. Ivanov
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Novel mitigators of hedge fund managers' fraud
Journal of Economic CriminologyThis article aims to contribute to the limited pool of solutions designed to deter or mitigate hedge fund manager fraud and reduce the associated costs to investors and other hedge fund industry stakeholders.
Majed R. Muhtaseb
doaj +1 more source
"El enigmático mundo de los hedge funds: beneficios y riesgos"
Revista de Fomento Social, 2008 Reseña de la obra: NOGUER, Marta (2008) El enigmático mundo de los “hedge funds”: beneficios y riesgos. Barcelona, La Caixa, 36 pp.
Julio Rueda Dotor
doaj +1 more source
International Journal of Financial Studies, 2020 Operational risk management remains a major concern for financial institutions. Indeed, institutions are bound to manage their own funds to hedge this risk. In this paper, we propose an approach to allocate one’s own funds based on a combination of
Mohamed Habachi, Saâd Benbachir
doaj +1 more source