Results 41 to 50 of about 105,747 (297)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Investment Compliance in Hedge Funds using Zero Knowledge Proofs
The Journal of The British Blockchain Association, 2021 Financial Regulation is a form of compliance system that subjects financial institutions to certain requirements and restrictions. Investment Compliance is an example that involves investment restrictions and monitoring on behalf of investors.
Komal Kalra +2 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
THE EFFECT OF HEDGE FUNDS ON THE TRANSFORMATION OF THE WORLD ECONOMIC RELATIONS
Мир новой экономики, 2018 Today, hedge funds are some of the most effective financial players able to show high earnings despite the crisis in the global economy and international financial markets. However, their work iscontroversial: often the high yield means the specific ways
FEODOR ALEKSANDROVICH Smirnov
doaj
Investment Management Strategy in Financial Markets
ECONOMICS, 2018 The subject matter of this research is investment management and its forms practiced in developed financial markets. The goal of this research is to elaborate on the strategies and characteristics of investment companies, hedge funds, venture capital ...
Vunjak Nenad +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
International Journal of Financial Studies, 2017 In this study, we attempt to identify the asset which has the best hedging characteristics against inflation. We study stock, bond, commodity, real estate and oil indexes. We also study these indexes tracking exchange traded funds (ETFs) to determine the
Stoyu I. Ivanov
doaj +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Novel mitigators of hedge fund managers' fraud
Journal of Economic CriminologyThis article aims to contribute to the limited pool of solutions designed to deter or mitigate hedge fund manager fraud and reduce the associated costs to investors and other hedge fund industry stakeholders.
Majed R. Muhtaseb
doaj +1 more source
International Journal of Financial Studies, 2020 Operational risk management remains a major concern for financial institutions. Indeed, institutions are bound to manage their own funds to hedge this risk. In this paper, we propose an approach to allocate one’s own funds based on a combination of
Mohamed Habachi, Saâd Benbachir
doaj +1 more source