Results 331 to 340 of about 201,870 (394)

Endoparasites of European hedgehogs (Erinaceus europaeus) in Germany and their zoonotic potential: proposed Capillaria ovoreticulata genetically identified as Capillaria putorii. [PDF]

Parasit Vectors
Schütte K, Springer A, Brandes F, Reuschel M, Fehr M, Kern A, Strube C.   +6 more
europepmc   +1 more source

The Prognostic Value of the Hedgehog Signaling Pathway in Ovarian Cancer. [PDF]

Int J Mol Sci
Salman ND, Hanker LC, Győrffy B, Bartha Á, Proppe L, Götte M.   +5 more
europepmc   +1 more source

Community‐informed and codesigned research to understand the impacts of railways on wildlife

Conservation Biology, EarlyView.
Abstract Trains cause mortalities of several animal species, but the ecological impacts of railways are understudied. Most research on wildlife–train collisions has focused on large mammals, but understanding railway‐specific risks for underrepresented taxa, especially vulnerable species, is important for developing effective mitigation strategies ...
Kyle D. Vincent, Jacqueline D. Litzgus, Steven J. Kell, Cory L. Kozmik, Angela Belleau, Jesse N. Popp   +5 more
wiley   +1 more source

When G Protein-Coupled Receptor Signaling Meets the Primary Cilium: Implications for Sonic Hedgehog Signaling. [PDF]

Bioessays
Kim SE.
europepmc   +1 more source

Implication of GPRASP2 in the Proliferation and Hair Cell‐Forming of Cochlear Supporting Cells

Cell Proliferation, EarlyView.
Schematic diagram of GPRASP2‐mediated SCs proliferation and HCs formation. GPRASP2 deficiency results in increased lysosomal degradation of SMO. GPRASP2‐mediated SMO/GLI1 signalling promotes SC proliferation, which contributes to HC formation. GPRASP2‐mediated SMO/β‐catenin signalling is implicated in HCs fate specification and differentiation ...
Jing Cai, Kun Huang, Wenrui Li, Tianming Wang, Shen Yue, Zhibin Chen, Guangqian Xing, Qinjun Wei, Jun Yao, Xin Cao   +9 more
wiley   +1 more source

Engineering Intervertebral Disc Regeneration: Biomaterials, Cell Sources and Animal Models

Cell Proliferation, EarlyView.
This review highlights the current tissue engineering approaches utilising biomaterials, animal models and cell sources for intervertebral disc regeneration and discusses future opportunities. ABSTRACT Intervertebral disc (IVD) degeneration is an age‐related problem triggering chronic spinal issues, such as low back pain and IVD herniation.
Sidong Yang, Farhad Soheilmoghaddam, Peter Pivonka, Joan Li, Samuel Rudd, Trifanny Yeo, Ji Tu, Yibo Zhu, Justin J. Cooper‐White   +8 more
wiley   +1 more source

GANT61 Modulates Autophagy and Lipid Metabolism in Ovarian Cancer. [PDF]

Cell Prolif
Pan Y, Chen L, Shen J, Hong S, Guan X, Ma X, Tang R, Lu M, Sun F, Shang S, Dai Y, Zhou Z, Zhang S, Yang J.   +13 more
europepmc   +1 more source

Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications

Cell Proliferation, EarlyView.
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su, Yanlin Li, Zihao Zhou, Bing Feng, Haiming Chen, Guangjuan Zheng   +5 more
wiley   +1 more source

Endocrine Resistance Score Based on Three Key Genes Predicts Prognosis and Reveals Potential Therapeutic Targets for ER+HER2− Breast Cancer

Cell Proliferation, EarlyView.
We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping, Lewei Zhu, Nian Chen, Xikun Liu, Jirui Zhong, Xiaoqing Sun, Hailin Tang, Kaiming Zhang   +7 more
wiley   +1 more source

Evaluation of Benzo[cd]indol-2(1H)-ones as Downstream Hedgehog Pathway Inhibitors. [PDF]

ChemistryOpen
Tsakoumagkos IA, Pasquer QTL, Guillod CL, Rossion C, Bagka M, Torche S, Sakata-Kato T, Chen JK, Hoogendoorn S.   +8 more
europepmc   +1 more source