Results 191 to 200 of about 2,340,031 (328)

Combined single cell and spatial transcriptome analysis reveals hedgehog pathway-related genes as potential therapeutic targets for cervical cancer

Cancer Treatment and Research Communications
Cervical cancer (CC) remains one of the most common and deadly malignancies among women worldwide, with exceptionally high morbidity and mortality rates.
Jing Zheng, Miaomiao Dou, Zhenzhen WU, Chunjie Zhang, Bo Yang, Zhijie Liu, Min Zhang, Fang Wang   +7 more
doaj  

RORα Coordinates Reciprocal Signaling in Cerebellar Development through Sonic hedgehog and Calcium-Dependent Pathways

, 2003
David Gold, Sung Hee Baek, Nicholas J. Schork, David W. Rose, DeLaine D. Larsen, Benjamin D. Sachs, Michael G. Rosenfeld, Bruce A. Hamilton   +7 more
openalex   +1 more source

Expression of Hedgehog Pathway Components in the Adult Colon [PDF]

, 2006
Gijs R. van den Brink, Maikel P. Peppelenbosch   +1 more
openalex   +1 more source

Activation of the hedgehog pathway in human hepatocellular carcinomas [PDF]

, 2006
Shuhong Huang, Jing He, Xiaoli Zhang, Yuehong Bian, Ling Yang, Guorui Xie, Kefei Zhang, Wendell W. Tang, Arwen A. Stelter, Qian Wang, Hongwei Zhang, Jingwu Xie   +11 more
openalex   +1 more source

Improving the integration of artificial intelligence into existing ecological inference workflows

Methods in Ecology and Evolution, EarlyView.
Abstract Artificial intelligence (AI) has revolutionised the process of identifying species and individuals in audio recordings and camera trap images. However, despite developments in sensor technology, machine learning and statistical methods, a general AI‐assisted data‐to‐inference pipeline has yet to emerge. We argue that this is, in part, due to a
Amber Cowans, Xavier Lambin, Darragh Hare, Chris Sutherland   +3 more
wiley   +1 more source

Molecular mechanisms of Eda‐mediated adaptation to freshwater in threespine stickleback

Molecular Ecology, EarlyView., 2023
Abstract A main goal of evolutionary biology is to understand the genetic basis of adaptive evolution. Although the genes that underlie some adaptive phenotypes are now known, the molecular pathways and regulatory mechanisms mediating the phenotypic effects of those genes often remain a black box.
Carlos E. Rodríguez‐Ramírez, Melanie Hiltbrunner, Verena Saladin, Stephanie Walker, Araxi Urrutia, Catherine L. Peichel   +5 more
wiley   +1 more source

The Sonic hedgehog pathway independently controls the patterning,proliferation and survival of neuroepithelial cells by regulating Gli activity [PDF]

, 2006
Jordi Cayuso, Fausto Ulloa, Barny Cox, James Briscoe, Elisa Martı́   +4 more
openalex   +1 more source

Safety and Tolerability of Sonic Hedgehog Pathway Inhibitors in Cancer

Drug Safety, 2019
R. Carpenter, Haimanti Ray
semanticscholar   +1 more source

Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments

Aging Cell, EarlyView.
The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel, J. Candia, C. Ubaida‐Mohien, T. Tanaka, A. Z. Moore, M. Zhu, G. Fantoni, S. Church, J. D'Agostino, J. Fan, N. Shehadeh, S. De, E. Lehrmann, M. Kaileh, E. Simonsick, R. Sen, J. M. Egan, L. Ferrucci   +17 more
wiley   +1 more source

Regulation and function of the sonic hedgehog (Shh) signal transduction pathway in isolated gastric parietal cells

, 2003
Vinzenz Stepan, Saravanan Ramamoorthy, H. Nitsche, Jung Park, Andrea Todisco   +4 more
openalex   +1 more source