Results 261 to 270 of about 2,340,031 (328)

Down-regulation of Sonic hedgehog signaling pathway activity is involved in 5-fluorouracil-induced apoptosis and motility inhibition in Hep3B cells

open access: diamond, 2008
Qiyu Wang   +7 more
openalex   +1 more source

Single‐Step Genome‐Wide Association Study of Factors for Evaluated and Linearly Scored Traits in Swedish Warmblood Horses

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Swedish Warmblood horses (SWB) are bred for show jumping and/or dressage with young horse test scores as indicator traits. This study aimed to investigate possible candidate genes and regions of importance for evaluated and linearly scored young horse test traits.
Anahit Nazari‐Ghadikolaei   +4 more
wiley   +1 more source

Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4

open access: bronze, 2008
Salvatore Cortellino   +11 more
openalex   +1 more source

Immunomodulation of salivary gland function due to cancer therapy

open access: yesOral Diseases, EarlyView.
Abstract Functional salivary glands (SG) are essential for maintaining oral health, and salivary dysfunction is a persistent major clinical challenge. Several cancer therapies also have off‐target effects leading to SG dysfunction. Recent advances highlight the role of SG immune populations in homeostasis, dysfunction and gland regeneration.
Ana C. Costa‐da‐Silva   +3 more
wiley   +1 more source

Metastatic Squamous Cell Carcinoma Treated With Pembrolizumab in a Patient With Xeroderma Pigmentosum

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT A 5‐year‐old male with xeroderma pigmentosum from Honduras presented with a rapidly growing mass on the left post‐auricular neck, associated with left‐sided hearing loss. MRI revealed a large mass with invasion of the external auditory canal, temporal bone, and metastasis to lymph nodes. Biopsy confirmed moderately differentiated squamous cell
Ngan Do   +4 more
wiley   +1 more source

Grape constituents for protection against photodamage to skin

open access: yesPhotochemistry and Photobiology, EarlyView.
Excessive exposure to solar ultraviolet radiation has a major negative impact on the health of skin. It causes sunburn, photoaging, keratinocyte carcinomas, and melanomas. Current methods of prevention have failed to stem the incidence of these adverse effects. Grapes are natural products that are being investigated as preventive agents that can impede
Yuri Kwon   +5 more
wiley   +1 more source

Inflammation and mechanical force‐induced bone remodeling

open access: yesPeriodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon   +6 more
wiley   +1 more source

(Re)wilding London: Fabric, politics, and aesthetics

open access: yesTransactions of the Institute of British Geographers, EarlyView.
Short Abstract Rewilding has become established as a new mode of nature conservation. Until recently, cities and the urban were neglected by rewilding discourse; the idea of urban rewilding seen as oxymoronic. Of late, however, there has been a shift, with growing enthusiasm amongst metropolitan authorities, civil society, and citizens in major cities.
Jonathon Turnbull   +2 more
wiley   +1 more source

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