Results 121 to 130 of about 223,583 (220)

The Biarylitides: Understanding the Structure and Biosynthesis of a Fascinating Class of Cytochrome P450 Modified RiPP Natural Products

open access: yesChemBioChem, Volume 26, Issue 7, April 1, 2025.
The biarylitides are fascinating RiPP natural products with small core peptides and diverse peptide crosslinks performed by cytochrome P450 enzymes. Here, we address the discovery and diversity of the biarylitides, methods to analyse these constrained cyclic peptides, the structures of the biarylitide P450 enzymes and address alternate catalytic ...
Leo Padva   +6 more
wiley   +1 more source

Unveiling the intriguing relationship: oncogenic KRAS, morphological shifts, and mutational complexity in pancreatic mucinous cystic neoplasms

open access: yesThe Journal of Pathology, Volume 265, Issue 4, Page 401-407, April 2025.
Abstract Pancreatic ductal adenocarcinoma (PDAC) often arises from preexisting cystic lesions such as intraductal papillary mucinous neoplasms (IPMN) and mucinous cystic neoplasms (MCN). This study investigated the molecular heterogeneity and mutational landscape of MCN in relation to PDAC, highlighting the significance of KRAS mutations in tumor ...
Lucas‐Alexander Schulte   +22 more
wiley   +1 more source

Blow-ups of minimal surfaces in the Heisenberg group

open access: yesAnalysis and Geometry in Metric Spaces
In this article, we revise Monti’s results on blow-ups of H-perimeter minimizing sets in Hn{{\mathbb{H}}}^{n}. Monti demonstrated that the Lipschitz approximation of the blow-up, after rescaling by the square root of the excess, converges to a limit ...
Yu Yonghao
doaj   +1 more source

Dark Dimension With (Little) Strings Attached

open access: yesFortschritte der Physik, Volume 73, Issue 4, April 2025.
Abstract A relation between dark energy and the scale of new physics in weakly coupled string theory is motivated. This mixing between infrared and ultraviolet physics leads to a unique corner for real‐world phenomenology: barring fine‐tunings, the authors are naturally led to the “dark dimension” scenario, a single mesoscopic extra dimension of micron
Ivano Basile, Dieter Lüst
wiley   +1 more source

Mikhlin-Type Hp Multiplier Theorem on the Heisenberg Group

open access: yesAxioms
The classical Fourier multiplier theorem by Mikhlin in Hardy spaces is extended to the Heisenberg group. The proof relies on the theories of atom and molecule functions and the property of special Hermite functions.
Jinsen Xiao, Jianxun He, Yingzhu Wu
doaj   +1 more source

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