Results 141 to 150 of about 164,924 (263)

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

scRNA‐Seq in Gastric Cancer Reveals Macrophage‐Derived C1q as a Diagnostic Marker

Cancer Science, EarlyView.
Single‐cell sequencing of GC analyzed the tumor microenvironment and discovered the C1QA+ TAMs subpopulation with immunosuppressive function. The role of C1q in the prognosis and diagnosis of GC was demonstrated through plasma and tumor tissue from the GC cohort.
Saisai Gong, Yupeng Zhao, Sheng Yang, Tong Liu, Chengyun Li, Yun Zhou, Geyu Liang   +6 more
wiley   +1 more source

Proportion of Screen‐Detected Gastrointestinal Cancers From the National Cancer Registry in Japan

Cancer Science, EarlyView.
Using the data from the Japanese National Cancer Registry, screen‐detected gastrointestinal cancers accounted for roughly 20% of all detected routes. We also found that the proportion of screen‐detected cancers was positively correlated with screening participation rates, supporting screen‐detected cancer proportion as a valuable indicator for ...
Ryuji Okamoto, Yukai Lu, Taisuke Ishii, Tomio Nakayama, Kensuke Shinmura, Tomonori Yano, Motoki Iwasaki   +6 more
wiley   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

Cancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren, Jing Jia, Tingting Li, Yiwei Li, Nanxiang Shen, Yun Shi, Zhe Wang, Hao Fan, Guangli Sun, Guanying Xiong, Gang Li, Rui Peng   +11 more
wiley   +1 more source

Abstracts [PDF]

Microbiota in Health and Disease, 2023
(EHMSG) European Helicobacter and Microbiota Study Group
doaj   +1 more source

Cross‐Reactivity of Treponema pallidum Polyclonal Antibody With Mycobacterium Species

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Introduction Mycobacteria are typically identified using the acid‐fast staining technique. Prior reports have observed cross‐reactivity of Treponema pallidum immunohistochemistry (IHC) with Mycobacterium species, particularly Mycobacterium leprae.
A. G. Zaladonis, S. Waseh, F. Ali, S. Huang, J. T. Hyde, M. Tuluc, J. B. Lee   +6 more
wiley   +1 more source

Prurigo Pigmentosa – an increasingly diagnosed dermatological condition associated with ketogenic diet

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
SUMMARY Prurigo pigmentosa (PP) is a rare inflammatory dermatosis, clinically characterized by intensely pruritic, erythematous papules and papulovesicles, with reticular hyperpigmentation upon healing. We herein report four cases in adults of different ethnic backgrounds, in which the disease was associated with ketogenic metabolic states due to ...
Antigona Aliu, Milan Vidakovic, Marcel Krauß, Julia Hyun, Frank Oellig, Thilo Gambichler, Valentina Laura Müller, Alexander Kreuter   +7 more
wiley   +1 more source

Effects of GLP‐1 agonists on the gut microbiota in type 2 diabetes mellitus: a systematic review

The FEBS Journal, EarlyView.
This systematic review evaluated 17 studies (12 preclinical and five clinical) on GLP‐1 receptor agonists in type 2 diabetes, demonstrating effects on the gut microbiota and metabolic improvement. The studies showed an increase in Bacteroidetes, Lactobacillus, and Akkermansia, and a reduction in Firmicutes.
Ranicleide Santos Dantas, Lucas Vinícius Souza Santos, André Gustavo Carvalho de Oliveira, Marina dos Santos Barreto, Deise Maria Rego Rodrigues Silva, Pedro Henrique Macedo Moura, Eloia Emanuelly Dias Silva, Ronaldy Santana Santos, Lucas Alves da Mota Santana, Rajiv Gandhi Gopalsamy, Adriana Gibara Guimarães, Lysandro Pinto Borges   +11 more
wiley   +1 more source

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

The FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa, Meng‐Lay Lin, Stuart A. C. McDonald   +2 more
wiley   +1 more source

Comprehensive and reproducible grading of the Updated Sydney System in gastric biopsies using artificial intelligence: multi‐pathologist validation and a reader study

Histopathology, EarlyView.
SydneyMTL is an interpretable multi‐task model providing four‐level grading for the five Sydney System attributes. By significantly improving diagnostic concordance and reducing reading time, it offers a robust clinical tool to alleviate pathologist workloads and standardize routine gastric biopsy screening.
Ho Heon Kim, Won Chan Jeong, Yuri Hwang, Gisu Hwang, Kyungeun Kim, Young Sin Ko   +5 more
wiley   +1 more source