Results 171 to 180 of about 358,107 (405)

Imposition of Different Optimizing Object with Non-Linear Constraints on Flux Sampling and Elimination of Free Futile Pathways [PDF]

arXiv, 2007
Constraint-based modeling has been widely used on metabolic networks analysis, such as biosynthetic prediction and flux optimization. The linear constraints, like mass conservation constraint, reversibility constraint, biological capacity constraint, can be imposed on linear algorithms.
arxiv  

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

Exploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu, Junya Feng, Jie Ma, Tixian Xiao, Wei Yuan   +4 more
wiley   +1 more source

Asociación de la lesión gástrica y la infección por helicobacter pylory en pacientes pediátricos Gastric lesion associated with the infection caused by Helicobacter Pylori in paediatric patients

Revista de Ciencias Médicas de Pinar del Río, 2009
Se realizó una investigación longitudinal y prospectiva, de las 249 biopsias gástricas diagnosticadas como lesión gástrica inflamatoria, a las cuales se les determinó la presencia de la infección por Helicobacter pylori, mediante la técnica de fucsina ...
Lissette Sixto Cordero, Maydelin Fernández González, Odalys Padrón Gonzáles, Dianelis Izquierdo Reina, Inalvis Cruz Hernández   +4 more
doaj  

The impact of dioctyl phthalate exposure on multiple organ systems and gut microbiota in mice

Heliyon, 2023
Dioctyl phthalate, commonly known as bis(2-ethylhexyl) phthalate (DEHP), is a widely used plasticizer in various industries and has been shown to directly or indirectly impact human health. However, there is a lack of comprehensive studies evaluating the
Qiang Zhang, Chunjing Qiu, Wenya Jiang, Pengya Feng, Xia Xue, Ihtisham Bukhari, Yang Mi, Pengyuan Zheng   +7 more
doaj  

Synthetic Biology‐Based Engineering Cells for Drug Delivery

Exploration, EarlyView.
Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi, Shuangshuang Hu, Xindi Qian, Wenlu Yan, Yaping Li   +4 more
wiley   +1 more source

The structure of His‐tagged Geobacillus stearothermophilus purine nucleoside phosphorylase reveals a `spanner in the works'

Acta Crystallographica Section F, Volume 78, Issue 12, Page 416-422, December 2022., 2022
The structure of Geobacillus stearothermophilus purine nucleoside phosphorylase, an enzyme of biocatalytic interest, is reported and was found to include the presence of an N‐terminal tag in the active site of each subunit that belongs to the other subunit in each dimer.
Fiona M. Given, Fuchsia Moran, Ashleigh S. Johns, James A. Titterington, Timothy M. Allison, Deborah L. Crittenden, Jodie M. Johnston   +6 more
wiley   +1 more source

The Helicobacter pylori AI-Clinician: Harnessing Artificial Intelligence to Personalize H. pylori Treatment Recommendations [PDF]

arXiv
Helicobacter pylori (H. pylori) is the most common carcinogenic pathogen worldwide. Infecting roughly 1 in 2 individuals globally, it is the leading cause of peptic ulcer disease, chronic gastritis, and gastric cancer. To investigate whether personalized treatments would be optimal for patients suffering from infection, we developed the H.
arxiv  

Impact of Maternal Helicobacter pylori Infection on Trace Elements (Copper, Iron and Zinc) and Pregnancy Outcomes [PDF]

, 2010
Background: H. pylori infection has been suggested to interfere with micronutrient metabolism and influence pregnancy outcomes. Objectives: This study therefore seeks to document the prevalence of H.
Akubugwo, EI, Ugwuja, EI
core  

Berries: Health Effects via Modulation of the Gut Microbiota

Food Frontiers, EarlyView.
ABSTRACT Berries are widely regarded as beneficial foods, rich in polyphenols, flavonoids, and other bioactive compounds that could positively influence human health. Although the gut microbiota plays a crucial role in metabolism and physiology of humans, the interaction between berries and human gut microbiota activity remains unclear.
Manjin Xu, Yunfeng Xu, Lizhi Wu, Huixia Niu, Bei Gao, Kai Sun, Xueqing Li, Mingluan Xing, Zhe Mo, Zhijian Chen, Pengcheng Tu, Xiaoming Lou   +11 more
wiley   +1 more source

Zooplankton act as cruise ships promoting the survival and pathogenicity of pathogenic bacteria

Microbiology and Immunology, Volume 66, Issue 12, Page 564-578, December 2022., 2022
Abstract Bacteria in general interact with zooplankton in aquatic ecosystems. These zooplankton–bacterial interactions help to shape the bacterial community by regulating bacterial abundances. Such interactions are even more significant and crucially in need of investigation in the case of pathogenic bacteria, which cause severe diseases in humans and ...
Ishara U. Perera, So Fujiyoshi, Yukiko Nishiuchi, Toshihiro Nakai, Fumito Maruyama   +4 more
wiley   +1 more source