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Results 91 to 100 of about 57,656 (254)

Factors Associated With Omalizumab Response in Chronic Spontaneous Urticaria: Are There Age‐Related Differences?

Acta Paediatrica, EarlyView.
ABSTRACT Aim This study aimed to explore clinical and laboratory markers of omalizumab response in paediatric and adult chronic spontaneous urticaria (CSU) patients. Methods The study included 32 children and 67 adults with CSU receiving omalizumab, and 29 paediatric and 30 adult healthy controls; associations with treatment response were evaluated ...
Güler Yıldırım Nalbant +14 more
wiley +1 more source

Evaluation of the Rapid Urease Test (RUT) Device for Rapid Diagnosis of Helicobacter pylori in Middle-Aged and Elderly Taiwanese Patients

Microorganisms
The rapid urease test (RUT) is a reliable method for diagnosing Helicobacter pylori infections in endoscopy suites; however, there is a need for tests with enhanced sensitivity and faster results.
Kuan-Yi Yu +6 more
doaj +1 more source

Clinical trial: The Effect on Intragastric pH and Pharmacokinetics of the PCAB Linaprazan Glurate in Healthy Subjects After Repeat‐Dose Administration for up to 14 Days

Alimentary Pharmacology &Therapeutics, EarlyView.
In this Phase 1 study, linaprazan glurate (LG) demonstrated rapid onset of intragastric acid suppression, achieving a pH > 4 within 10 to 60 min, and maintained pH control, with a 24‐h pH > 4 holding time ratio above 95% at 50 mg and 75 mg twice‐daily doses. AUC and Cmax of linaprazan, the main metabolite of LG, increased in proportion to LG dose.
Kajsa Larsson +7 more
wiley +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff +3 more
wiley +1 more source

Progress in immunotherapy for Helicobacter pylori infections

Frontiers in Cellular and Infection Microbiology
Helicobacter pylori is the most common cause of chronic gastric mucosal infections worldwide. The current global H. pylori infection rate is estimated at 50%. Untreated H. pylori colonization may lead to gastritis, peptic ulcers, and malignancies such as
Wane Zhong +4 more
doaj +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

Cancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren +11 more
wiley +1 more source

Evolution of Bacterial Yield and Antimicrobial Resistance in Chronic Rhinosinusitis Patients in a Dedicated Sinus Centre

Clinical Otolaryngology, EarlyView.
ABSTRACT Background Antibiotics are frequently prescribed for acute exacerbations of chronic rhinosinusitis (CRS). However, antimicrobial resistance presents a challenge for the ongoing and future management of CRS patients. Objective This study aims to examine the current and past microbiological yield and antimicrobial resistance profile in a ...
Timoleon Siempis, Zhu Yeap, Shifa Ali, Carl M. Philpott +3 more
wiley +1 more source

Cross‐Reactivity of Treponema pallidum Polyclonal Antibody With Mycobacterium Species

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Introduction Mycobacteria are typically identified using the acid‐fast staining technique. Prior reports have observed cross‐reactivity of Treponema pallidum immunohistochemistry (IHC) with Mycobacterium species, particularly Mycobacterium leprae.
A. G. Zaladonis +6 more
wiley +1 more source

Prurigo Pigmentosa – an increasingly diagnosed dermatological condition associated with ketogenic diet

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
SUMMARY Prurigo pigmentosa (PP) is a rare inflammatory dermatosis, clinically characterized by intensely pruritic, erythematous papules and papulovesicles, with reticular hyperpigmentation upon healing. We herein report four cases in adults of different ethnic backgrounds, in which the disease was associated with ketogenic metabolic states due to ...
Antigona Aliu +7 more
wiley +1 more source

3rd Brazilian consensus on Helicobacter pylori 3º Consenso Brasileiro para Estudo do Helicobacter pylori

Arquivos de Gastroenterologia, 2013
Significant progress has been obtained since the Second Brazilian Consensus Conference on Helicobacter pylori Infection held in 2004, in São Paulo, SP, Brazil, and justify a third meeting to establish updated guidelines on the current management of ...
Luiz Gonzaga Coelho +5 more
doaj

helicobacter pylori
gastritis
helicobacter

stomach neoplasms
zoonosis
h. pylori

diagnosis
gastric ulcer
infections