Results 91 to 100 of about 56,367 (254)

Meta‐Analysis: Prevalence of Non‐Helicobacter pylori, Non‐NSAID Peptic Ulcer Disease

Alimentary Pharmacology &Therapeutics, EarlyView.
A meta‐analysis of 92 studies including 60,816 patients found that non‐H. pylori, non‐NSAID represent a non‐negligible but heterogeneous component of peptic ulcer disease. Among bleeding ulcers, this proportion increased over time, potentially reflecting evolving etiologic patterns beyond H. pylori infection and NSAID exposure.
Jun Watanabe, Hiromi Sekiguchi, Takeshi Kanno, Keigo Misawa, Satoshi Sato, Yuhong Yuan, Paul Moayyedi, Tomonori Yano, Atsushi Masamune, Tomoari Kamada   +9 more
wiley   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Evaluation of the Rapid Urease Test (RUT) Device for Rapid Diagnosis of Helicobacter pylori in Middle-Aged and Elderly Taiwanese Patients

Microorganisms
The rapid urease test (RUT) is a reliable method for diagnosing Helicobacter pylori infections in endoscopy suites; however, there is a need for tests with enhanced sensitivity and faster results.
Kuan-Yi Yu, Yu-Chuan Chuang, Tien-Yu Huang, Hua-Kang Chou, Ying-Tsang Lu, Juin-Hong Cherng, Cheng-Che Liu   +6 more
doaj   +1 more source

Gastric Mucosal Molecular Alterations and Multimodal Field‐Based Risk Models for Gastric Cancer Development

Cancer Science, EarlyView.
DNA methylation in non‐neoplastic background gastric mucosa reflects cumulative inflammatory and exposure‐related field changes before cancer develops. Combining methylation with clinical, endoscopic, histological, and emerging multimodal information may refine calibrated gastric cancer risk prediction and support risk‐adapted personalized endoscopic ...
Genki Usui, Atsushi Kaneda
wiley   +1 more source

circMAN1A2 as an Isoform‐Resolved Circular RNA Hub in Cancer

Cancer Science, EarlyView.
circMAN1A2 as an isoform‐resolved circular RNA hub in cancer. circMAN1A2 is generated by back‐splicing of MAN1A2 pre‐mRNA, with alternative circularization producing multiple isoforms, including the predominant circMAN1A2(2–5). Its mechanistic interfaces include miRNA‐associated regulation, RBP binding/proteostasis control, BSJ‐mediated RNA–RNA pairing,
Hanyu Shang, Hui Wang, Yonghang Xu, Lingyun Geng, Yanqing Wang   +4 more
wiley   +1 more source

Prurigo Pigmentosa – an increasingly diagnosed dermatological condition associated with ketogenic diet

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
SUMMARY Prurigo pigmentosa (PP) is a rare inflammatory dermatosis, clinically characterized by intensely pruritic, erythematous papules and papulovesicles, with reticular hyperpigmentation upon healing. We herein report four cases in adults of different ethnic backgrounds, in which the disease was associated with ketogenic metabolic states due to ...
Antigona Aliu, Milan Vidakovic, Marcel Krauß, Julia Hyun, Frank Oellig, Thilo Gambichler, Valentina Laura Müller, Alexander Kreuter   +7 more
wiley   +1 more source

Extranodal Marginal Zone Lymphoma: Integrating Etiology, Microenvironment, and Genetics Into Clinical Decision‐Making

European Journal of Haematology, EarlyView.
ABSTRACT Extranodal marginal zone lymphoma (EMZL) represents a unique paradigm among indolent B‐cell neoplasms, in which lymphomagenesis is frequently driven by chronic antigenic stimulation within tissue‐specific microenvironments. Persistent infectious or autoimmune triggers promote the development of ectopic lymphoid tissue and sustain B‐cell ...
Mamdouh Skafi, Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +15 more
wiley   +1 more source

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

The FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa, Meng‐Lay Lin, Stuart A. C. McDonald   +2 more
wiley   +1 more source

Small Bowel Lesions and Bleeding Risk in Hemodialysis Patients: A Narrative Review

Hemodialysis International, EarlyView.
ABSTRACT Background Gastrointestinal bleeding is very common among hemodialysis patients. This high bleeding risk is caused by uremic platelet dysfunction, vascular fragility, intradialytic hemodynamic instability, and widespread antithrombotic therapy.
Andreas Smyrlis, Konstantia Kantartzi, Konstantinos Mimidis, Stylianos Panagoutsos   +3 more
wiley   +1 more source

Evidence Map Analysis on Randomized Controlled Trials: Chinese Patent Medicines and Classic Traditional Chinese Medicine Prescriptions

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Objectives To evaluate the status and methodological quality of randomized controlled trials published in 2024 on Chinese patent medicines and Classic Traditional Chinese Medicine Prescriptions, providing evidence for clinical practice and policy.
Xiaolei Wu, Yazi Zhang, Jinji Zhao, Haiyin Hu, Alice Josephine Fauci, Myeong Soo Lee, Zifan Sang, Danni Li, Ni Qin, Tianhui Sun, Jiaqi Yu, Menglong Shi, Boli Zhang, Junhua Zhang, Zhaochen Ji   +14 more
wiley   +1 more source