Results 261 to 270 of about 3,272,245 (333)

Efficacy of High‐Dose Intravenous Anakinra in Pediatric TAFRO Syndrome: Report of Two Cases and Literature Review

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly) syndrome is a rare, life‐threatening inflammatory condition linked to infections, neoplasms, and idiopathic multicentric Castleman disease. Interleukin (IL)‐6 inhibitors are the primary treatment, but refractory cases require alternatives. This
Serena Palmeri   +10 more
wiley   +1 more source

Potential Kidney Risks Associated With Clinical Doses of Omeprazole: In Vivo and In Vitro Studies

open access: yesClinical and Experimental Pharmacology and Physiology, Volume 52, Issue 8, August 2025.
Omeprazole decreases cell proliferation and viability by disrupting gene expression; thus, the long‐term use of omeprazole may increase inflammation and environmental susceptibility. These findings provide valuable insights for the clinical use of omeprazole, highlighting the need for careful consideration of its effects in the kidney.
Zibo Xiong   +7 more
wiley   +1 more source

Antibiotic stress affects the secretion and physicochemical features of extracellular vesicles produced by Helicobacter pylori. [PDF]

open access: yesJ Antimicrob Chemother
Krzyżek P   +9 more
europepmc   +1 more source

Clonal Hematopoiesis and Solid Cancers

open access: yesCancer Science, Volume 116, Issue 8, Page 2055-2063, August 2025.
This review explores the relationship between clonal hematopoiesis and solid cancers. Clonal hematopoiesis mutations influence the tumor microenvironment by altering immune regulation, inflammation, and angiogenesis. Understanding these mutations has important clinical implications, including their role in prognosis, treatment response, and potential ...
Yen T. M. Nguyen   +3 more
wiley   +1 more source

Gastric Signet Ring Cell Carcinoma in a Helicobacter pylori‐Positive 10‐Year‐Old Boy: A Case Report and Literature Review

open access: yesCancer Science, Volume 116, Issue 8, Page 2064-2074, August 2025.
A case report and literature review of pediatric gastric signet ring cell carcinoma (GSRCC) suggest the potential role of H. pylori infection in the pathogenesis of pediatric GSRCC. ABSTRACT Gastric cancer is rare in pediatric populations, with gastric signet ring cell carcinoma (GSRCC) being an exceptionally infrequent subtype.
Xiaoxuan Li   +11 more
wiley   +1 more source

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