Results 41 to 50 of about 38,033 (184)

South African Propolis: Anti‐Helicobacter pylori Activity, Chemistry, and Toxicity

Chemistry &Biodiversity, EarlyView.
ABSTRACT Propolis, a resin‐like substance produced by bees, has previously shown antimicrobial activity against the ulcer‐causing gut pathogen Helicobacter pylori. South African propolis, however, was yet to be investigated. This study aimed to investigate a comprehensive range of South African propolis for its antimicrobial activity against H.
Sarhana Dinat, Ané Orchard, Efficient Ncube, Weiyang Chen, Alvaro Viljoen, Sandy van Vuuren   +5 more
wiley   +1 more source

Helicobacter pylori infection and arteriosclerosis

Journal of Education, Health and Sport, 2019
Rakszewska Tamara, Alzubedi Adam. Helicobacter pylori infection and arteriosclerosis. Journal of Education, Health and Sport. 2019;9(4):503-506. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.2651708 http://ojs.ukw.edu.pl/index.php/johs/article/view/6851 The journal has had 7 points in Ministry of Science and Higher Education ...
Adam Alzubedi, Tamara Rakszewska
openaire   +5 more sources

Citrus Flavonoids as Antimicrobials

Chemistry &Biodiversity, EarlyView.
Citrus flavonoids are powerful and versatile antimicrobials whose mechanism of action often involves disruption of the bacterial membrane, thereby minimizing antimicrobial resistance. This study provides a unified perspective. ABSTRACT Citrus flavonoids are highly bioactive compounds exerting numerous health benefits including anticancer, antioxidant ...
Rosaria Ciriminna, Giovanna Li Petri, Giuseppe Angellotti, Rafael Luque, Anne‐Sylvie Fabiano Tixier, Francesco Meneguzzo, Mario Pagliaro   +6 more
wiley   +1 more source

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

Cytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar, Joyeeta Chakraborty, Pananghat Gayathri, Ramanujam Srinivasan   +3 more
wiley   +1 more source

Synthesis of Rhamnose‐Modified Lewis‐X‐Containing Saponins

European Journal of Organic Chemistry, EarlyView.
The synthesis of triterpenoid saponins bearing a Lewis‐X trisaccharide analogue, in which the fucose residue is replaced by a rhamnose, is presented. These saponins, designed as negative controls in dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing nonintegrin‐targeted therapeutic applications, are prepared through iterative and ...
Oscar Javier Gamboa Marin, Nitish Verma, Maude Cloutier, Charles Gauthier   +3 more
wiley   +1 more source

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

Exploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu, Junya Feng, Jie Ma, Tixian Xiao, Wei Yuan   +4 more
wiley   +1 more source

Eradication of Helicobacter pylori infection

The Kaohsiung Journal of Medical Sciences, 2013
AbstractEradication of Helicobacter pylori infection has become an important issue recently, because this bacterial species cluster can cause many gastrointestinal diseases. Elevated antibiotic resistance is related to an increasing failure rate of H. pylori eradication. Standard triple therapy is still the first‐line therapy; however, according to the
Chao-Hung Kuo, Huang-Ming Hu, Tzung-Shiun Wu, Fu-Chen Kuo   +3 more
openaire   +4 more sources

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

The impact of a high‐fat diet on liver health in pregnant mice and their offspring: The role of the gut‐liver axis

iMetaOmics, EarlyView.
The study investigated the longitudinal effects of normal and high‐fat diet, showing their differential effects on gut microbiota diversity and gut metabolites, with the latter having a significant impact on increasing liver inflammation and gut microbiota and metabolites disruption.
Qian Gong, Yufei Zhang, Juxiong Liu, Shuai Yuan, Huijie Hu, Yu Cao, Shoupeng Fu, Wenjin Guo   +7 more
wiley   +1 more source

Elevated tissue transglutaminase immunoglobulin A: Celiac disease or polytypic plasmacytosis?

JPGN Reports, EarlyView.
Abstract We report a case of an adolescent girl post cardiac transplant with hypergammaglobulinemia and presumed celiac disease (CD), who had a persistently elevated anti‐tissue transglutaminase immunoglobulin A despite a gluten free diet. Refractory CD and Crohn's disease were excluded.
Andrew Turunen, Aisha Ahmed, Philip Thrush, Paula North, Ankur Chugh   +4 more
wiley   +1 more source