Results 41 to 50 of about 58,926 (216)

Inhibitors of Helicobacter pylori protease HtrA found by "virtual ligand" screening combat bacterial invasion of epithelia

, 2011
Background: The human pathogen Helicobacter pylori (H. pylori) is a main cause for gastric inflammation and cancer. Increasing bacterial resistance against antibiotics demands for innovative strategies for therapeutic intervention.
Löwer, Martin, Schneider, Gisbert, Petra Schneider, Hoy Benjamin, Löwer Martin, Martin Löwer, Tim Geppert, Geppert, Tim, Silja Wessler, Wessler Silja, Schneider, Petra, Geppert Tim, Gisbert Schneider, Benjamin Hoy, Hoy, Benjamin, Weßler, Silja, Schneider Petra, Schneider, Gisbert (Prof. Dr.), Schneider Gisbert   +18 more
core   +1 more source

Dietary amelioration of Helicobacter infection [PDF]

Nutrition Research, 2015
We review herein the basis for using dietary components to treat and/or prevent Helicobacter pylori infection, with emphasis on (a) work reported in the last decade, (b) dietary components for which there is mechanism-based plausibility, and (c) components for which clinical results on H pylori amelioration are available.
Jed W, Fahey, Katherine K, Stephenson, Alison J, Wallace   +2 more
openaire   +2 more sources

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Canadian Helicobacter pylori Consensus Conference Update: Infections in Adults

, 1999
The first Canadian Helicobacter pylori Consensus Conference took place in April 1997. The initial recommendations of the conference were published in early 1998.
CA Fallone, ABR Thomson, Canadian Helicobacter Study Group, RH Hunt   +3 more
core   +1 more source

Helicobacter cinaedi Induced Typhlocolitis in Rag-2-Deficient Mice [PDF]

, 2015
Background Helicobacter cinaedi, an enterohepatic helicobacter species (EHS), is an important human pathogen and is associated with a wide range of diseases, especially in immunocompromised patients.
Feng, Yan, Rickman, Barry H, James G. Fox, Barry Rickman, Shen, Zeli, Zeli Shen, Yan Feng, Fox, James G   +7 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Helicobacter pylori Infections in Children

Antibiotics, 2023
In the context of epidemiology, host response, disease presentation, diagnosis, and treatment management, the manifestation of Helicobacter pylori (H. pylori) infection diverges between children and adults. H.
Julie Nguyen, Kallirroi Kotilea, Patrick Bontems, Veronique Yvette Miendje Deyi   +3 more
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Advances in Gastric Cancer Research: Insights Into Carcinogenesis, the Tumor Microenvironment, Metastasis, and Factors Influencing Prognosis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba, Takatsugu Ishimoto, Yoshifumi Baba, Hiromitsu Hayashi, Masaaki Iwatsuki   +4 more
wiley   +1 more source

Xstainer: A Novel Virtual Staining Tool Powered by Advanced Deep Learning Techniques

Advanced Intelligent Systems, EarlyView.
Xstainer is a deep learning–based virtual staining framework that converts hematoxylin and eosin‐stained whole slide images into multiple histochemical stains, including Masson's trichrome, Periodic acid‐Schiff, Jones methenamine silver, and Toluidine blue.
Fatma Nur Kinali, Derya Demir, Kutsev B. Ozyoruk, Yasin Almalioglu, Emre C. Kose, Drew F. K. Williamson, Gurdeniz Serin, G. Evren Keles, Banu S. Kumbaraci, Ceren Utku, Uguray P. Hacisalihoglu, Ilknur Turkmen, Figen Ozturk, Kayhan Basak, Yavuz Nuri Ertas, Mehmet Turan   +15 more
wiley   +1 more source