Results 171 to 180 of about 236,492 (306)

Preconception maternal gut dysbiosis affects enteric nervous system development and disease susceptibility in offspring via the GPR41–GDNF/RET/SOX10 signaling pathway

open access: yesiMeta, EarlyView.
Preconception administration of antibiotics to female mice reduces the abundance of Limosilactobacillus reuteri in the maternal gut microbiota during pregnancy, subsequently affecting propionate levels. Decreased propionate levels downregulated the expression of Gdnf/Ret/Sox10 mediated by GPR41, leading to abnormal development of the enteric nervous ...
Cunzheng Zhang   +10 more
wiley   +1 more source

Gut microbiota in cancer: From molecular mechanisms to precision medicine applications

open access: yesiMeta, EarlyView.
The gut microbiota–cancer interaction functions through multi‐level biological mechanisms, forming the basis for both diagnostic and therapeutic applications. Current technical and biological challenges drive the field toward precision medicine approaches, aiming to integrate multi‐dimensional data for optimized, personalized cancer treatments.
Weihua Xiao   +8 more
wiley   +1 more source

Helicobacter pylori Prevalence and Impact: A Histology-Based Report About Children from an Endemic Country

open access: yesInternational Journal of General Medicine, 2020
Fareed Khdair Ahmad,1 Tariq N Aladily,2 Motaz Altamimi,3 Maher Ajour,3 Nisreen Alsaber,3 Mohamed Rawashdeh1 1Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, School of Medicine, The University of Jordan, Amman ...
Khdair Ahmad F   +5 more
doaj  

Physiologically Based Pharmacokinetic Modeling and Simulation to Support a Change in the FDA‐Labeled Dosing Frequency of RHB‐105 Low‐Dose Rifabutin Triple Therapy for Helicobacter pylori Eradication

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Patient adherence is vital for Helicobacter pylori eradication. Simplifying therapy dosing schedules may promote patient adherence, enhance treatment success rates, and help mitigate the development of antibiotic resistance. We aimed to assess plasma and intragastric rifabutin, amoxicillin, and omeprazole concentrations comparing two dosing ...
Nimish Vakil   +6 more
wiley   +1 more source

Integrative nomogram model based on anoikis-related genes enhances prognostic evaluation in colorectal cancer

open access: yesHeliyon
Background: Revealing the role of anoikis resistance plays in CRC is significant for CRC diagnosis and treatment. This study integrated the CRC anoikis-related key genes (CRC-AKGs) and established a novel model for improving the efficiency and accuracy ...
Yuexiao Zhang   +5 more
doaj  

Seroprevalence and Socio-demographic Factors of Helicobacter pylori Infection in Patients with Dyspepsia in Kalibaru Primary Health Care North Jakarta

open access: yesActa Medica Indonesiana, 2015
Aim: to identify the seroprevalence and its association with socio-demographic factors of Helicobacter pylori infection. Methods: a cross-sectional study was performed in 111 patients with dyspepsia (according to ROME III) who got treatment at Kalibaru ...
Nikko Darnindro   +3 more
doaj  

Urine-Based ELISA for the Detection of Helicobacter pylori IgG Antibody and Comparison with Other Invasive Methods.

open access: bronze, 1970
Md Din-ul Islam   +5 more
openalex   +2 more sources

Standardized biopsy protocols improve adherence to eosinophilic esophagitis and celiac disease endoscopic biopsy guidelines

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Optimal detection of eosinophilic esophagitis (EoE) and celiac disease (CeD) requires appropriate sampling of the upper gastrointestinal tract during endoscopy. However, endoscopic biopsy guidelines are poorly followed in clinical practice.
Sharon S. Tam   +3 more
wiley   +1 more source

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