Results 271 to 280 of about 276,829 (341)

Gankyrin‐Protein Interactions in GI Cancers: A Novel Target of New Therapeutics

Chronic Diseases and Translational Medicine, Volume 11, Issue 4, Page 269-278, December 2025.
ABSTRACT Gankyrin (PSMD10) is a 25 kDa oncogenic protein and regulatory subunit of the 26S proteasome, characterized by a sevenfold ankyrin repeat domain. Gankyrin is overexpressed in various malignancies, particularly gastrointestinal (GI) cancers. Gankyrin contributes to tumorigenesis by modulating key signaling pathways and engaging in oncogenic ...
Shuang Li, Yuky Lam, Aaron Muth, Zhe‐Sheng Chen, Shanzhi Wang   +4 more
wiley   +1 more source

Cyclooxygenase-2 expression and apoptosis in Helicobacter pylori-infected human gastric epithelial cells

, 2002
Jung Mogg Kim, Joo‐Sung Kim, Hyun‐Chae Jung, In-Sung Song, Chung-Yong Kim   +4 more
openalex   +1 more source

Setting up JBrowse 2 for Visualizing Genome Synteny

Current Protocols, Volume 5, Issue 12, December 2025.
Abstract JBrowse 2 is an open‐source genome browser that provides unique features for visualizing syntenic relationships between multiple genomes. This article describes a protocol for setting up synteny views in JBrowse 2, using an assembly‐to‐assembly whole‐genome alignment example.
Colin Diesh, Garrett Stevens, Scott Cain, Lincoln Stein, Ian Holmes   +4 more
wiley   +1 more source

A Prospective Assessment of Helicobacter pylori Eradication Regimens in Treatment-Naïve Patients With Peptic Ulcer Disease. [PDF]

Cureus
Nawaz Z, Atta A, Ameen S, Hussain S, Yousaf J, Akbar AA, Batool SW, Elrefae A, Ishtiaq H, Khattak MI, Mirza TI.   +10 more
europepmc   +1 more source

Epigenetic dynamics in gastric cancer precancerous lesions: From molecular mechanisms to precision risk stratification

Clinical and Translational Discovery, Volume 5, Issue 6, December 2025.
Gastric precancerous lesions undergo dynamic epigenetic alterations—including DNA methylation, 5‐hydroxymethylcytosine, non‐coding RNAs, and RNA editing—throughout the Correa's cascade. The integration of these multi‐omics epigenetic signatures facilitates non‐invasive risk stratification, which guides personalised surveillance strategy and targeted ...
Kewei Ma, Guanqi Shi, Xiao Li, Wanwei Zheng, Zhongguang Luo   +4 more
wiley   +1 more source

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source

Targeted detection of <i>Helicobacter pylori</i> resistance to clarithromycin and levofloxacin using single-cell Raman spectroscopy. [PDF]

J Med Microbiol
Wu Z, Li X, Dou X, Yang H, Zhang X, Xiong D, Gao X.   +6 more
europepmc   +1 more source

Transforming Infection Management with Organic Bioelectronic Materials and Devices

Electroanalysis, Volume 37, Issue 12, December 2025.
Conducting polymers bridge the gap between abiotic and biotic environments by using ions and electrons as charge carriers. In this review, we explore their roles in infection modeling, where conducting polymers modulate host–bacteria interactions; infection detection, employing wired and wireless biosensors for real‐time monitoring of bacterial growth;
Atefeh Shafaat, Delphine Greco, Susanne Löffler, Agneta Richter‐Dahlfors   +3 more
wiley   +1 more source

Corrigendum to “Hydrogel‐Transformable Probiotic Powder for Targeted Eradication of Helicobacter pylori with Enhanced Gastric Mucosal Repair and Microbiota Preservation”

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Yongkang Lai, Hanchun Shen, Shige Wang, Yongliang Ouyang, Xinyuan Zhang, Bin Hu, Xiaoyi Zhang, Guisheng Li, Lizhi Xu, Jiulong Zhao   +9 more
wiley   +1 more source