Results 41 to 50 of about 69,057 (254)

Recent acquisition of Helicobacter pylori by Baka Pygmies [PDF]

, 2013
Both anatomically modern humans and the gastric pathogen Helicobacter pylori originated in Africa, and both species have been associated for at least 100,000 years. Seven geographically distinct H.
AB Migliano, Armand Nkwescheu, Ayas Maady, B Linz, B Pakendorf, Bodo Linz, C Batini, C Ehret, CM Schlebusch, CY Tay, D Falush, D Falush, D Schoenbrun, Daniel Eibach, Daniel Falush, DD Palmer, DM Behar, DM Magalhaes Queiroz, DY Graham, E Patin, G Brusotti, G Hellenthal, G Jobb, G Morelli, Gil McVean, JC Assob, JG Kusters, Jose Siri, JZ Li, KA Jolley, L Excoffier, L Naduvilezhath, L Quintana-Murci, LA Zhivotovsky, M Achtman, M Guisset, M Jakobsson, M Kawai, Mark Achtman, MC Campbell, MF Rupnow, MF Rupnow, MF Rupnow, MJ Hamilton, MK Gonder, NA Drake, NA Rosenberg, NS Becker, P Librado, RE Pounder, RN Ndip, RN Ndip, RR Hudson, RR Hudson, RW Frenck Jr, S Breurec, S Latifi-Navid, S Schwarz, SA Tishkoff, Sandra Nell, SC Schuster, Sebastian Suerbaum, T Wirth, TH Farag, V Kuete, V Montano, Valeria Montano, W Delport, Wael F. Elamin, X Didelot, Y Chen, Y Moodley, Y Moodley, Yoshan Moodley   +73 more
core   +3 more sources

A fekélybetegség és a stressz [PDF]

, 2015
The discovery that Helicobacter pylori infection is the major cause of peptic ulcer disease revolutionised our views on the etiology and treatment of the disease.
Herszényi, László, Juhász, Márk, Mihály, Emese, Tulassay, Zsolt   +3 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Polarised epithelial monolayers of the gastric mucosa reveal insights into mucosal homeostasis and defence against infection [PDF]

, 2018
Objective Helicobacter pylori causes life-long colonisation of the gastric mucosa, leading to chronic inflammation with increased risk of gastric cancer.
Berger, H., Boccellato, F., Denecke, C., Goosmann, C., Imai-Matsushima, A., Meyer, T., Morey, P., Ordemann, J., Sanchez, G., Schmid, M., Woelffling, S.   +10 more
core   +3 more sources

Helicobacter pylori Infection in Pediatrics

Helicobacter, 2014
AbstractThis review concerns important pediatric studies published from April 2013 to March 2014. New data on pathogenesis have demonstrated that Th1 type cytokine secretion at the gastric level is less intense in children compared with adults. They have also shown that the most significant risk factor for Helicobacter pylori infection is the parents ...
Iwańczak, Barbara, Francavailla, Ruggiero   +1 more
openaire   +3 more sources

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Impact of Maternal Helicobacter pylori Infection on Trace Elements (Copper, Iron and Zinc) and Pregnancy Outcomes [PDF]

, 2010
Background: H. pylori infection has been suggested to interfere with micronutrient metabolism and influence pregnancy outcomes. Objectives: This study therefore seeks to document the prevalence of H.
Akubugwo, EI, Ugwuja, EI
core  

Increased circulating regulatory T cells and decreased follicular T helper cells are associated with colorectal carcinogenesis

Frontiers in Immunology
ObjectiveColorectal cancer (CRC) is the third most prevalent cancer worldwide and is associated with high morbidity and mortality rates. Colorectal carcinogenesis occurs via the conventional adenoma-to-carcinoma and serrated pathways.
Qiao Meng, Qiao Meng, Yang Zhao, Miao Xu, Pingzhang Wang, Jun Li, Rongli Cui, Weiwei Fu, Weiwei Fu, Shigang Ding, Shigang Ding   +10 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source