Results 71 to 80 of about 6,329 (210)
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen +9 more
wiley +1 more source
Background: Various ways of treating H.pylori infection are reported, such as triple-therapy and quadruple therapy for two weeks. Some side effects have been seen during these treatments, besides Helicobacter pylori becoming resistant to these ...
Shahriar Nikpour +4 more
doaj
Single‐Cell Transcriptomics and Deep Learning Link N‐(2‐Furoyl) Glycine to GLRX3 in Gastric Cancer
ABSTRACT Gastric cancer remains a health burden, and its metabolic drivers are poorly defined. N‐(2‐furoyl) glycine, a circulating metabolite, has been implicated in tumor biology. We investigated its causal role in gastric cancer and the underlying mechanism.
Yingyi Zhang +4 more
wiley +1 more source
This study developed and externally validated a questionnaire‐based household risk model to identify families with multiple Helicobacter pylori infections. Using only noninvasive, readily available household information, the model showed good discrimination and enabled a family‐based screening strategy that substantially improved detection efficiency ...
Yifan Qiu +9 more
wiley +1 more source
Background: Helicobacter pylori causes motor, secretory, and inflammatory gastrointestinal disorders and therefore the term “functional” has been questioned when referring to dyspepsia associated with this bacterium.
J.L. Rodríguez-García +1 more
doaj +1 more source
Advances and challenges in experimental models for Epstein–Barr virus research
Abstract Epstein–Barr virus (EBV), the first identified human oncovirus, is a ubiquitous γ‐herpesvirus etiologically linked to diverse malignancies, lymphoproliferative disorders, and autoimmune diseases. Experimental models are pivotal for unraveling the infection and pathogenesis mechanisms, life cycle regulation, as well as development and ...
Gulimire Wufuer +5 more
wiley +1 more source
Background: Helicobacter pylori infection is common in children and causes a number of diseases including peptic ulcers, iron deficiency anemia, decreased growth rate, and gastrointestinal cancer. This study assessed the effects of various factors on the
Amir Hossein Moslehi +3 more
doaj
RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run +7 more
wiley +1 more source
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao +8 more
wiley +1 more source
Helicobacter pylori infection: an overview [PDF]
For many decades the dictum 'no acid, no ulcer' dominated thinking on the pathogenesis of peptic ulcer. When I was a medical student, not surprisingly, the standard therapy for a peptic ulcer was an antacid possibly combined with carbenoxolone. As a medical registrar, I was involved in the early studies with H2-receptor antagonists which, at the time ...
openaire +2 more sources

