Results 261 to 270 of about 292,669 (354)

Pharmacokinetics, Safety, and Skin Irritation and Sensitization Potential of Clascoterone Cream in Early‐Phase Clinical Study Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano   +8 more
wiley   +1 more source

Elucidating reactive sugar-intermediates by mass spectrometry. [PDF]

open access: yesCommun Chem
Chang CW   +8 more
europepmc   +1 more source

Charge State Influence on Stability and Isomerism in Dehydrogenated PAHs: Insights from Anthracene, Acridine, and Phenazine

open access: yesChemPhysChem, Volume 26, Issue 6, March 15, 2025.
The ionization of anthracene, acridine, and phenazine has been explored, along with the removal of one and two hydrogen atoms, to provide valuable information for astrochemists and to understand the behavior of the resulting structures and their electronic reorganization. Abstract In this study, we systematically explored the stability and isomerism of
Khaldia Zghida   +3 more
wiley   +1 more source

Threshold Photoelectron Spectroscopy of Monosulfur Monofluoride

open access: yesChemPhysChem, EarlyView.
Threshold photoelectron spectroscopy with vacuum ultraviolet synchrotron radiation refines spectroscopic constants and energies of the fundamental monosulfur monofluoride (SF) species. The high accuracy adiabatic ionization energy derived will serve as benchmark for calculation of heat of formation of SF and SF+.
Ugo Jacovella   +7 more
wiley   +1 more source

Helium Incorporation into Scandium Fluoride, a Model Negative Thermal Expansion Material. [PDF]

open access: yesChem Mater
Ma S   +6 more
europepmc   +1 more source

Intensification of Ethylene Carbonate Synthesis via Microwave‐Induced Phase‐Change Cycles

open access: yesChemSusChem, EarlyView.
Microwave‐assisted heating under ambient pressure reflux conditions is applied to intensify the transesterification of ethylene glycol with dimethyl carbonate. The proposed method enhances energy efficiency and product yield compared to conventional heating, enabling lower catalyst loading, reduced process time, and significantly decreased energy ...
Ioannis Papaioannou   +5 more
wiley   +1 more source

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