Results 141 to 150 of about 81,764 (264)

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Hellenism and the Shaping of the Byzantine Empire [PDF]

, 2010
Mittal, Rakesh
core   +1 more source

Tillich's Schellingian Styles

The Heythrop Journal, EarlyView.
Abstract In this essay I contend that, whatever one might say about F.W.J. Schelling's historical and conceptual influence on Paul Tillich's doctrines, the overall style of Tillich's project can helpfully be dubbed Schellingian to the extent it mixes together discourses, genres, and vocabularies into an ever‐expanding whole. To the extent that anything
Daniel Whistler
wiley   +1 more source

A Review of the Evolution of Research on the Size of Children's Drawings in Relation to Their Expressed Emotion About the Depicted Topic: 1988–2023

International Journal of Art &Design Education, EarlyView.
Abstract This narrative review examines the relationship between the size of children's drawings and their expressed emotions about the depicted subjects, focusing on research conducted between 1988 and 2023. The studies are presented chronologically to demonstrate how researchers have progressively addressed methodological challenges identified in ...
Elpida Kypraiou, Fotini Bonoti
wiley   +1 more source

Towards a Consultative Union? Unpacking Parliamentary Stances on Citizen Participation in EU Policy‐Making

JCMS: Journal of Common Market Studies, EarlyView.
Abstract Recent developments within the European Union (EU) reveal a notable ‘citizen turn’ marked by initiatives aimed at enhancing citizen engagement with EU institutions through deliberative mechanisms. Whilst existing scholarship has extensively examined political elites' perceptions of these participatory tools at the national level, the policy ...
Karolina Borońska‐Hryniewiecka, Jan Kotýnek Krotký   +1 more
wiley   +1 more source

Book review: A. M. Eckstein, Mediterranean Anarchy, Interstate War, and the Rise of Rome [PDF]

, 2008
Erskine, Andrew
core   +1 more source

Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis, Erkan Alpsoy, Florian Anzengruber, Matthias Augustin, Falk G. Bechara, Pierre‐André Becherel, Farida Benhadou, Vincenzo Bettoli, Joana Cabete, Raffaele Dante Caposiena Caro, Antonella Di Cesare, Giovanni Damiani, Valentina Dini, Evangelos J. Giamarellos‐Bourboulis, Krisztián Gáspár, Katalin Glasenhardt, Philippe Guillem, Ariela Hafner, Barbara Horvath, John R. Ingram, Vaiva Jarienè, Gregor B. E. Jemec, Alexander Katoulis, Natalia Kirsten, Georgios Kokolakis, Piotr K. Krajewski, Aikaterini I. Liakou, Flavia Manzo Margiotta, Angelo V. Marzano, Antonio Martorell, Lukasz Matusiak, Dillon Mintoff, Alejandro Molina Leyva, Andreas Pinter, Anna Pirogova, Maurizio Podda, Francesca Prignano, Jorge Romani, Marco Romanelli, Elia Rosi, Samed Sahin, Ditte M. L. Saunte, Sylke Schneider‐Burrus, Mariano Suppa, Jacek Szepietowski, Andrea Szegedi, Simon Francis Thomsen, Thrasyvoulos Tzellos, Anastasia Trigoni, Hessel H. Van Der Zee, Kelsey Van Straalen, Skaidra Valiukevičiene, Eva Vilarrasa, Esther von Stebut, Christos C. Zouboulis   +54 more
wiley   +1 more source

Bimekizumab efficacy using IHS4 outcomes in hidradenitis suppurativa: Results from BE HEARD I and II

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The majority of bimekizumab‐treated patients shifted from severe to mild and moderate IHS4 stages, and nearly 25% achieved an IHS4 of 0 by Week 48. Bimekizumab led to clinically meaningful improvements across IHS4 outcome measures. These data highlight an opportunity to address the need for effective treatments against draining tunnels.
Thrasyvoulos Tzellos, Evangelos J. Giamarellos‐Bourboulis, Kelsey R. van Straalen, Antonio Martorell, Brian Kirby, Afsaneh Alavi, Koremasa Hayama, Saakshi Khattri, Wayne Gulliver, Christopher J. Sayed, Leah Davis, Robert L. Rolleri, Christina Crater, Ingrid Pansar, Jérémy Lambert, Christos C. Zouboulis   +15 more
wiley   +1 more source

Genomic and proteomic insights into hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou, Emmanouil Stylianakis, Isis Ricaño‐Ponce, Nick Keur, Theodora Kanni, Dimitra Stergianou, Mihai G. Netea, Vinod Kumar, Evangelos J. Giamarellos‐Bourboulis   +8 more
wiley   +1 more source

Glass vessels from the Persian and Hellenistic Administrative Building at Tel Kedesh, Israel [PDF]

, 2017
Berlin, Andrea M., Herbert, Sharon, Larson, Katherine A.   +2 more
core