Results 31 to 40 of about 875 (154)

Proteinvermittelte Kupfer‐Redoxregulation: Rolle von Disulfidbrücken und allosterischer Modulation

Angewandte Chemie, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann, Chang Liu, Xue Wang, Hegne Pupart, Xun Sun, Jan Gui‐Hyon Dreiser, Peep Palumaa, Qinghua Liao, Matthias Krack, Jinghui Luo   +9 more
wiley   +1 more source

Liganden der Lipidtasche induzieren allosterische Modulation der Proteindynamik im Bereich des aktiven Zentrums der Proteinkinase p38α

Angewandte Chemie, EarlyView.
Bei der Suche nach neuen allosterischen Stellen in der Serin/Threonin‐Kinase p38α deckt die NMR‐Spektroskopie eine dynamische Kopplung zwischen dem katalytischen Zentrum und der Lipidtasche auf. Die Ergebnisse offenbaren bewegungsbezogene Interdependenzen, die entfernte Regionen des Enzyms miteinander verbinden, was die Lipidtasche als ...
Sara Medina Gómez, Laurin T. Homberg, Mike Bührmann, Daniel Rauh, Rasmus Linser   +4 more
wiley   +1 more source

Genome-wide SNP detection, validation, and development of an 8K SNP array for apple. [PDF]

PLoS ONE, 2012
As high-throughput genetic marker screening systems are essential for a range of genetics studies and plant breeding applications, the International RosBREED SNP Consortium (IRSC) has utilized the Illumina Infinium® II system to develop a medium- to high-
David Chagné, Ross N Crowhurst, Michela Troggio, Mark W Davey, Barbara Gilmore, Cindy Lawley, Stijn Vanderzande, Roger P Hellens, Satish Kumar, Alessandro Cestaro, Riccardo Velasco, Dorrie Main, Jasper D Rees, Amy Iezzoni, Todd Mockler, Larry Wilhelm, Eric Van de Weg, Susan E Gardiner, Nahla Bassil, Cameron Peace   +19 more
doaj   +1 more source

Wasserstoffaktivierung über Dihydrid‐Bildung an einem Rh1/Fe3O4(001)‐Einzelatomkatalysator

Angewandte Chemie, EarlyView.
Die Deuterium‐ (Wasserstoff‐)Adsorption am Einzelatomkatalysator Rh1/Fe3O4(001) induziert keinen D‐ (H‐)Spillover auf den reduzierbaren Fe3O4‐Träger. Stattdessen bildet sich eine Rh1‐Dihydrid‐Spezies (Rh−2D bzw. Rh−2H), dessen Wasserstoff beim Tempern desorbiert. ZUSAMMENFASSUNG Die Wasserstoffaktivierung ist ein zentraler Schritt in der katalystischen
Chunlei Wang, Panukorn Sombut, Lena Puntscher, Nail Barama, Maosheng Hao, Florian Kraushofer, Jiri Pavelec, Matthias Meier, Florian Libisch, Michael Schmid, Ulrike Diebold, Cesare Franchini, Gareth S. Parkinson   +12 more
wiley   +1 more source

Bridging change and project management: A review and future research directions

Project Leadership and Society
The fundamental purpose of a project is to implement change, aiming for the transition from an existing state to a desired future state. However, project management studies primarily focus on the design and implementation of the project deliverable and ...
Elina Jääskä, Kirsi Aaltonen, Liina Hellens, Jaakko Kujala   +3 more
doaj   +1 more source

Identification of Mendel's white flower character. [PDF]

PLoS ONE, 2010
The genetic regulation of flower color has been widely studied, notably as a character used by Mendel and his predecessors in the study of inheritance in pea.We used the genome sequence of model legumes, together with their known synteny to the pea ...
Roger P Hellens, Carol Moreau, Kui Lin-Wang, Kathy E Schwinn, Susan J Thomson, Mark W E J Fiers, Tonya J Frew, Sarah R Murray, Julie M I Hofer, Jeanne M E Jacobs, Kevin M Davies, Andrew C Allan, Abdelhafid Bendahmane, Clarice J Coyne, Gail M Timmerman-Vaughan, T H Noel Ellis   +15 more
doaj   +1 more source

MOFs als neue katalytische Plattform für kovalente adaptive Netzwerke: Katalyse trifft Verstärkung

Angewandte Chemie, EarlyView.
Eine neu entwickelte, heterogene, katalytische Plattform für kovalente adaptive Netzwerke (CANs) wird vorgestellt. Dies wird erreicht durch die Immobilisierung von Basen mit geringem Molekulargewicht auf metallorganischen Gerüstverbindungen (MOFs). Der erhaltene Katalysator UiO‐TBD profitiert von der hohen Beladungskapazität von MOFs und demonstriert ...
Simon Renner, Roman Korotkov, Inge Mühlbacher, Markus Alfreider, Daniel Kiener, Johannes Liebhart, Oskar Paris, Christian Slugovc, Sandra Schlögl, Elisabeth Rossegger   +9 more
wiley   +1 more source

Efficacy of the Intervention Against the Stigmatization of Men With Eating Disorders in Primary Healthcare (iSMEsH): Results From a Randomized Waitlist‐Controlled Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) in men are underdiagnosed and undertreated, partly due to stigma hindering help‐seeking. This randomized waitlist‐controlled study tested the efficacy of the iSMEsH online anti‐stigma intervention targeting German general practitioners (GPs) and medical students.
Martin S. Lehe, Georg Halbeisen, Sabine Steins‐Loeber, Georgios Paslakis   +3 more
wiley   +1 more source

Biodegradable Coatings with Essential Oils for Combating Papaya Anthracnose: State of the Art and Perspectives

Food Bioengineering, EarlyView.
ABSTRACT Papaya (Carica papaya L.) production and marketability are strongly constrained by postharvest diseases, with anthracnose caused by Colletotrichum spp. representing the most significant threat. Traditional control relies on synthetic fungicides, which, although effective, face challenges such as the development of pathogen resistance ...
Raul Coimbra Miranda, Zandia Maria de Souza Nascimento, Beni Jequicene Mussengue Chaúque, Hellen Kempfer Philippsen, Lúcia de Fátima Henriques Lourenço, Consuelo Lúcia Sousa de Lima   +5 more
wiley   +1 more source

A walk in the park—Identifying healthy greenspaces using scents

PLANTS, PEOPLE, PLANET, EarlyView.
As urbanisation accelerates globally, access to nature is increasingly recognised as vital for public health and wellbeing. We captured and analysed plant‐emitted airborne ‘scent signatures’ across Oxford's urban greenspaces to assess their potential health relevance.
William T. Kay, Anya Lindström Battle, Mahal Humberstone, Molly Tucker, Kieran E. Storer, Geoffrey Kite, Katherine Willis   +6 more
wiley   +1 more source