Results 11 to 20 of about 9,702 (195)

A Review of HELLP Syndrome [PDF]

Journal of Perinatology, 1999
HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome is a variant of severe preeclampsia which is associated with substantial maternal and perinatal morbidity and mortality. As with preeclampsia, the etiology and pathogenesis of HELLP syndrome is not completely understood.
W M, Curtin, L, Weinstein
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Comparison of clinical features and pregnancy outcomes in early- and late-onset preeclampsia with HELLP syndrome: a 10-year retrospective study from a tertiary hospital and referral center in China

BMC Pregnancy and Childbirth, 2022
Background Early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE) are different subtypes of preeclampsia. We conducted this study to analyze the similarities and differences in the clinical features and pregnancy outcomes in EO- and LO-PE ...
Boya Li, Huixia Yang
doaj   +1 more source

Transcriptome analysis of placentae reveals HELLP syndrome exhibits a greater extent of placental metabolic dysfunction than preeclampsia

Hypertension in Pregnancy, 2021
Objective: The association between HELLP syndrome and preeclampsia has been investigated with conflicting conclusions. This study is to investigate the pathogenesis underlying these two diseases by analyzing placental transcriptome.
Lili Gong, Huanqiang Zhao, Yutong Cui, Xiaotian Li   +3 more
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Clinical diagnosis and treatment of “atypical” HELLP syndrome

Gynecology and Obstetrics Clinical Medicine, 2022
HELLP syndrome is regarded as one of the most serious manifestations of preeclampsia, but approximately 15% of patients with HELLP syndrome have no clinical manifestations of preeclampsia; furthermore, although most cases of HELLP syndrome occur after 34
Ying-dong He, Hui-xia Yang
doaj   +1 more source

Longitudinal changes in placental biomarkers in women with early versus late placental dysfunction

Hypertension in Pregnancy, 2019
Objective: To evaluate longitudinal changes of angiogenic biomarkers in early- (EO-PD) versus late-onset (LO-PD) placental dysfunction. Methods: Serum PlGF and sFlt-1 measured at different intervals in EO-PD (n= 43), LO-PD (n= 31) and controls (n = 133).
Manouk L. E. Hendrix, Kirsten C. M. Palm, Sander M. J. Van Kuijk, Otto Bekers, Marc E. A. Spaanderman, Judith A. P. Bons, Salwan Al-Nasiry   +6 more
doaj   +1 more source

Acute kidney injury during pregnancy leads to increased sFlt-1 and sEng and decreased renal T regulatory cells in pregnant rats with HELLP syndrome

Biology of Sex Differences, 2020
Background The incidence of acute kidney injury (AKI) during pregnancy precedes a high maternal mortality rate of 20–40%. AKI during pregnancy has multiple etiologies; however, the more common are maternal hypertensive disorders, which include ...
Jamie Szczepanski, Shauna-Kay Spencer, Ashley Griffin, Teylor Bowles, Jan Michael Williams, Patrick B. Kyle, John Polk Dumas, Sarah Araji, Kedra Wallace   +8 more
doaj   +1 more source

COVID-19: A Cause of HELLP Syndrome? A Case Report

International Journal of Women's Health, 2022
Ebubekir Arslan Mogadishu Somalia Turkish Training and Research Hospital, Mogadishu, 2526, SomaliaCorrespondence: Ebubekir Arslan, Tel +905317936501, Email ebuarslan@hotmail.comPurpose: There are still many unexplained points about how COVID-19 affects ...
Arslan E
doaj  

HELLP Syndrome and the Anaesthetist [PDF]

Obstetric Anesthesia Digest, 1988
Summary Four pregnant patients are described who had varying signs of pre‐eclampsia plus haemolysis, elevated liver enzymes and a low platelet count. Two of the patients presented without hypertension and all posed considerable diagnostic difficulties, with problems in clinical management.
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Placental sFLT1 is associated with complement activation and syncytiotrophoblast damage in preeclampsia

Hypertension in Pregnancy, 2019
The immune complement system protects against pathogens; however, excess activation results in disease like hemolytic uremic syndrome, a clinical imitator of preeclampsia. Vascular endothelial factor (VEGF) protects against aberrant complement activation
Ai-ris Yonekura Collier, Zsuzsanna Zsengeller, Elizabeth Pernicone, Saira Salahuddin, Eliyahu V. Khankin, S. Ananth Karumanchi   +5 more
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Ketonuria and HELLP syndrome

BMJ Case Reports, 2009
We recently managed a patient with the HELLP syndrome (Haemolysis, Elevated Liver enzymes and Low Platelet count) where there was a delay in diagnosis due to gastroenteritis. This case also reiterates the varied or lack of symptomatology in patients developing HELLP and obscuring the initial diagnosis.
Phanendra Kumar, Gubbala, Mahantesh, Karoshi, Faris, Zakaria   +2 more
openaire   +3 more sources