Results 91 to 100 of about 98,160 (283)

Cardiovascular disease and type 2 diabetes in evolutionary perspective: A critical role for helminths?

Evolution, Medicine and Public Health, 2016
Heart disease and type 2 diabetes are commonly believed to be rare among contemporary subsistence-level human populations, and by extension prehistoric populations.
M. Gurven, B. Trumble, J. Stieglitz, Aaron D. Blackwell, D. Michalik, C. Finch, H. Kaplan   +6 more
semanticscholar   +1 more source

Hedgehogs and Angiostrongylus cantonensis: Uncovering the Role of Atelerix albiventris in the Parasite Life Cycle

Integrative Zoology, EarlyView.
ABSTRACT The ongoing invasion of the zoonotic parasite Angiostrongylus cantonensis threatens humans, other mammals, and birds. In Mallorca, neurological disorders associated with this parasite are increasingly reported in free‐living Algerian hedgehogs, Atelerix algirus, raising public health concerns.
Anna Šipková, Kristýna Javorská, Lucia Anettová, Divakaran Pandian, Petr Cibulka, Jana Kačmaříková, Ladislav Novotný, David Modrý   +7 more
wiley   +1 more source

Factors associated with the performance and cost-effectiveness of using lymphatic filariasis transmission assessment surveys for monitoring soil-transmitted helminths: a case study in Kenya. [PDF]

, 2015
Transmission assessment surveys (TAS) for lymphatic filariasis have been proposed as a platform to assess the impact of mass drug administration (MDA) on soil-transmitted helminths (STHs).
Assefa, Aurenhammer, Bergquist, Birgit Nikolay, Brooker, Brooker, Charles S. Mwandawiro, Chu, de Silva, Edwards, Gunawardena, Hall, Hugh J. W. Sturrock, Jennifer L. Smith, Jimmy Kihara, Jovani, Levecke, Linard, Liya Assefa, McCarthy, Minetti, Mwandawiro, Mwandawiro, Nikolay, Njenga, Olives, Patil, Pullan, Sammy M. Njenga, Simon J. Brooker, Smith, Solomon, Sturrock, Sturrock, Sturrock   +34 more
core   +1 more source

Needle in a Haystack: A Droplet Digital Polymerase Chain Reaction Assay to Detect Rare Helminth Parasites Infecting Natural Host Populations

Molecular Ecology Resources, EarlyView.
ABSTRACT Helminths infect humans, livestock, and wildlife, yet remain understudied despite their significant impact on public health and agriculture. Because many of the most prevalent helminth‐borne diseases are zoonotic, understanding helminth transmission among wildlife could improve predictions and management of infection risks across species.
Chloe A. Fouilloux, Eric Neeno‐Eckwall, Ipsita Srinivas, Jonathan S. Compton, Josh Sampson, Jesse Weber, Cole Wolf, Amanda Hund, John Berini III, Heather Alexander, Emma Choi, Daniel I. Bolnick, Jessica L. Hite   +12 more
wiley   +1 more source

Enrichment of Helminth Mitochondrial Genomes From Faecal Samples Using Hybridisation Capture

Molecular Ecology Resources, EarlyView.
ABSTRACT New approaches are urgently needed to enrich rare or low‐abundant DNA in complex samples. Soil‐transmitted helminths (STHs) inhabit heterogeneous environments, including the gastrointestinal tract of their host as adults and are excreted as eggs and larvae in faeces, complicating our understanding of their biology and the use of genetic tools ...
Marina Papaiakovou, Andrea Waeschenbach, Roy M. Anderson, Piet Cools, Zeleke Mekonnen, D. Timothy J. Littlewood, Cinzia Cantacessi, Stephen R. Doyle   +7 more
wiley   +1 more source

Ecology of the Squirrel Treefrog (Hyla squirella) in Southern Arkansas [PDF]

, 2014
We conducted an ecological study of the Squirrel Treefrog, Hyla squirella near El Dorado, Union Co., Arkansas from May-Oct. 2013. We extended the known distribution by ~2 km and documented the first breeding occurring on 28 May and the first ...
Bursey, C. R., Connior, M. B., Fulmer, T., McAllister, C. T., Trauth, S. E.   +4 more
core   +3 more sources

Interactions between multiple helminths and the gut microbiota in wild rodents

Philosophical Transactions of the Royal Society B: Biological Sciences, 2015
The gut microbiota is vital to host health and, as such, it is important to elucidate the mechanisms altering its composition and diversity. Intestinal helminths are host immunomodulators and have evolved both temporally and spatially in close ...
J. Kreisinger, G. Bastien, H. Hauffe, J. Marchesi, S. Perkins   +4 more
semanticscholar   +1 more source

CT‐P39 Compared With Reference Omalizumab in Chronic Spontaneous Urticaria: Results From a Double‐Blind, Randomized, Active‐Controlled, Phase 3 Study

Allergy, EarlyView.
This study investigated the therapeutic equivalence of CT‐P39 (an omalizumab biosimilar) and EU‐approved reference omalizumab (ref‐OMA) in patients with chronic spontaneous urticaria. Therapeutic equivalence between CT‐P39 and ref‑OMA (300 mg) was demonstrated by the primary endpoint – confidence intervals of the treatment difference in mean change ...
Sarbjit S. Saini, Marcus Maurer, Yevgeniya Dytyatkovska, Ewa Springer, Maria Ratkova, Borislava Krusheva, Chun Wook Park, Grazyna Pulka, Marta Chełmińska, Adam Reich, Sunghyun Kim, Keumyoung Ahn, Suyoung Kim, Sewon Lee, Jieun Ka, Jongho Kim, Clive Grattan   +16 more
wiley   +1 more source

A Novel Non-invasive Method to Detect RELM Beta Transcript in Gut Barrier Related Changes During a Gastrointestinal Nematode Infection [PDF]

, 2019
Currently, methods for monitoring changes of gut barrier integrity and the associated immune response via non-invasive means are limited. Therefore, we aimed to develop a novel non-invasive technique to investigate immunological host responses ...
Affinass, Nicole, Ahmed, Norus, Hartmann, Susanne, Heitlinger, Emanuel, Jarquin, Victor Hugo, Jost, Jenny, Kühl, Anja A., Steinfelder, Svenja, Xenophontos, Natasa   +8 more
core   +4 more sources

Allergic Reactivity and Memory Occur Independently of Sequential Switching Through IgG1

Allergy, EarlyView.
Sequential switching through IgG1 is not required to produce IgE with sufficient allergen‐binding affinity to cause anaphylaxis against food allergens. Sequential switching through IgG1 does not confer a competitive advantage to become an IgE‐expressing cell.
Joshua F. E. Koenig, Adam K. Wade‐Vallance, Rodrigo Jiménez‐Saiz, Kelly Bruton, Siyon Gadkar, Emily Grydziuszko, Tina D. Walker, Melissa E. Gordon, Amy E. Gillgrass, Justin J. Taylor, Susan Waserman, Manel Jordana   +11 more
wiley   +1 more source