Results 111 to 120 of about 79,245 (300)

Sex‐Dependent Influence of Major Histocompatibility Complex Diversity on Fitness in a Social Mammal

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Parasite infections affect males and females differently across a wide range of species, often due to differences in immune responses. Generally, females tend to have stronger immune defences and lower parasite loads than males. The major histocompatibility complex (MHC) plays a crucial role in the adaptive immune response, and extensive ...
Nadine Schubert   +8 more
wiley   +1 more source

Field studies of Culex mosquitoes in Tanzania and Kenya: A systematic review motivated by changing Rift Valley fever virus transmission patterns

open access: yesMedical and Veterinary Entomology, EarlyView.
There were 275 studies reporting Culex abundance, 17 of which explicitly stated the motivation for the study was RVFV. Despite most studies being motivated by other topics, there was good coverage of studies reporting mosquito sampling in areas associated with the risk of RVFV outbreaks. Studies were c.
Catherine Andrews   +3 more
wiley   +1 more source

Zoonotic helminth infections in rodents and shrews from southern Philippines: Unforeseen One Health hazards

open access: yesVeterinary Integrative Sciences
Rodents are known as reservoirs of different zoonotic parasites. This study aimed to determine the occurrence of zoonotic helminths in rodents from different habitats in selected municipalities in Cotabato Province. A total of 120 rodents and shrews
Mary Joyce H. Matullano   +2 more
doaj   +1 more source

Immunization With Bovine Milk Casein Results in Enteric Nervous System Pathology in a Mouse Model of Neuroinflammation

open access: yesNeurogastroenterology &Motility, EarlyView.
Experimental study design. Mice were immunized with either α‐Lactalbumin or casein, and the resulting pathology of the enteric nervous system (ENS) was assessed using electron microscopy and immunofluorescence imaging. In vitro culture of isolated cells of the ENS was used to complement the in vivo findings.
Rittika Chunder   +5 more
wiley   +1 more source

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij   +7 more
wiley   +1 more source

Bacilli load in PTB- intestinal helminths co-infected and PTB non -infected patients at selected public health facilities in Jimma zone, Oromia, Ethiopia: comparative cross-sectional study

open access: yesBMC Infectious Diseases
Background Tuberculosis (TB) and intestinal helminths are diseases that pose a dual burden on public health in low-income countries. Previous studies have shown that helminths can affect the shedding of bacteria or the bacterial load in the sputum of ...
Melese Mekuria   +3 more
doaj   +1 more source

Highly efficient transgene‐free ErCas12a RNP‐protoplast genome editing and single‐cell regeneration in Nicotiana benthamiana for glyco‐engineering

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana serves as a unique platform for biopharmaceutical production, offering advantages such as efficient and scalable protein synthesis. In addition, custom N‐glycans can be engineered on biopharmaceutical glycoproteins. Yet, plant‐native glycosyltransferases and glycoside hydrolases need to be removed to prevent undesired ...
Lukas C. Blumberg   +8 more
wiley   +1 more source

Pharmacotherapy of helminth infection

open access: yesExpert Opinion on Pharmacotherapy, 2009
In the first decade of the 21st century, worm infections are still very common, especially--but not exclusively--in the developing world.To review the current pharmacotherapy of the major trematode, cestode and nematode infections of humans.A systematic search of the Cochrane Databank of Controlled Trials and PubMed with MeSH terms (anthelmint(*) or ...
openaire   +4 more sources

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