Results 31 to 40 of about 60,423 (192)

Helminth

, 2011
Strongyloides stercoralis, an intestinal nematode commonly known as the human threadworm, affects millions of people worldwide.(1) It is endemic in Southeast Asia, Latin America, sub-Saharan Africa, and parts of the southeastern USA.(2) In the USA, the highest prevalence rates are found in eastern Kentucky and rural Tennessee.
Grossman, Marc E., Fox, Lindy P., Kovarik, Carrie, Rosenbach, Misha   +3 more
openaire   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Forging a New Frontier: Antimicrobial Peptides and Nanotechnology Converging to Conquer Gastrointestinal Pathogens

Small, EarlyView.
This review explores the potential of antimicrobial peptides (AMPs) and nanotechnology for the treatment of gastrointestinal infections. It analyzes bacterial resistance mechanisms, the antimicrobial actions of AMPs, and advances in nanocarriers, such as lipid‐based, polymeric, metallic, and mesoporous silica systems, that enhance peptide protection ...
Christian Shleider Carnero Canales, Cesar Augusto Roque‐Borda, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Uner Josseph Pinto Apaza, Vanderson de Jesus Silva, Laura Maria Duran Gleriani Primo, Maura Jennifer Martínez‐Morales, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +10 more
wiley   +1 more source

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
A Tarkowski, AL Moncayo, AM Gan, B Min, Cathy Steel, CH Kuo, CM Steppan, D Artis, D Voehringer, DD Taub, DR Herbert, DR Herbert, DR Neill, Edward J. Pearce, F Chen, Gang Chen, GD Thomas, Graham Le Gros, H Helmby, HK Park, HS Jung, J Bethony, J Urban, J Wang, JA Jackson, Jessica C. Jang, JF Urban Jr, JI Odegaard, JJ Reece, Josiah I. Chung, JT Pesce, K Migita, KT Cuenco, L Boring, L Le Goff, L Patel, LC Osborne, M Lehrke, M Lehrke, M Qatanani, Mali Camberis, Mark A. Barnes, Meera G. Nair, MG Nair, MG Nair, MG Nair, Mitchell A. Lazar, MM Pirvulescu, MP Reilly, N Silswal, P Loke, PF Weller, Philip J. Cooper, PJ George, PJ Hotez, R Anuradha, RM Anthony, RT Semnani, RZ Yang, S Babu, S Babu, S Babu, S Babu, S Jiang, S Lee, Spencer H. Wang, Thomas B. Nutman, TT MacDonald, W He, Y Benomar, YY Hsieh   +70 more
core   +5 more sources

Genetic identification of gastrointestinal parasites in the world's most endangered ungulate, the hirola (Beatragus hunteri)

Veterinary Record, EarlyView.
Abstract Background The hirola (Beatragus hunteri) is the world's most critically endangered antelope. Its parasitic fauna has never been genetically characterised, raising questions about its possible role in the species' population decline. This study aimed to assess the presence of gastrointestinal parasites in hirolas and their transmission ...
Susana Remesar, David García‐Dios, Giovanni Forcina, Abdullahi H. Ali, Mathew Ndunda, Michael J. Jowers   +5 more
wiley   +1 more source

microRNAs of parasitic helminths – identification, characterization and potential as drug targets [PDF]

, 2014
microRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene regulation. They were first identified in the free-living nematode Caenorhabditis elegans, where the miRNAs lin-4 and let-7 were shown to be essential for regulating ...
Britton, Collette, Devaney, Eileen, Gillan, Victoria, Winter, Alan D.   +3 more
core   +1 more source

Variation in prevalence and intensity of macroparasites in moose and their interactions with winter tick load in eastern Canada

Wildlife Biology, EarlyView.
Wild animals are infected with a large diversity and abundance of parasites that can affect their behavior, growth, body condition, and ultimately their survival. Although the adverse effects of parasites and the mechanisms involved in the interactions between a host and its parasites are generally well studied, much less is known about the additive or
Catherine Pouchet, Christopher Fernandez‐Prada, Christian Dussault, Martin Leclerc, Jean‐Pierre Tremblay, Steeve D. Côté   +5 more
wiley   +1 more source

Gastrointestinal helminths in calves and cows in an organic milk production system [PDF]

, 2012
The main aim of this study was to determine the distribution of populations of gastrointestinal helminths in lactating crossbred cows and calves during the grazing season in an organic milk production system.
Amarante AFT, Athanasiadou S, Beasley AM, Busato A, D'Almeida TN, Dimander SO, Gasbarre LC, Gennari SM, Höglund J, Höglund J, Kaneene JB, Lima WS, Oliveira MC, Pimentel Neto M, Thamsborg SM, Thamsborg SM, Ueno H, Vaarst M, Vercruysse J, Weller RF   +19 more
core   +3 more sources

Why are our roe deer short of breath? – prevalence and promotive factors of lung parasites in roe deer Capreolus capreolus in south‐eastern Germany

Wildlife Biology, EarlyView.
The existence of bronchopulmonary nematodes in German roe deer Capreolus capreolus is well documented, with two types of lung parasites that have been described previously: Dictyocaulus capreolus and Varestrongylus capreoli. However, little is known about the impact of these parasites on their host animal or which parameters influence outbreak and ...
Tobias Wild, Christian Ehrmantraut, Sarah‐Alica Dahl, Felix Langer, Elisabeth Kiess, Kathrin Simon, Markus Meissner, Andreas König   +7 more
wiley   +1 more source

Does mass drug administration for the integrated treatment of neglected tropical diseases really work? Assessing evidence for the control of schistosomiasis and soil-transmitted helminths in Uganda [PDF]

, 2011
This paper was one of four papers commissioned to review the role of social sciences in NTD control by TDR, the Special Programme for Research and Training on Tropical Diseases, which is executed by WHO and co-sponsored by UNICEF, UNDP, the World Bank ...
A Dansio-Appiah, A Fenwick, A Fenwick, B Gryseels, B Gryseels, CJ Standley, D Engels, D Yu, DH Molyneux, DH Molyneux, EP Renne, FM Fleming, G Yamey, I Harper, J Hastings, J Utzinger, JH Kolaczinski, L Manderson, M Leach, M Parker, M Parker, M Parker, M Parker, M Yahya, MA Brady, Melissa Parker, MN Katabarawa, MN Katabarwa, N Rees, NB Kabatereine, NB Kabatereine, NB Kabatereine, PJ Hotez, PJ Hotez, PJ Lammie, RGN Lubanga, S Brooker, S Knopp, T Allen, T Allen, T Allen, T Allen, T Allen, T Allen, Tim Allen, TL-A Tchuente, U Amazigo, World Health Organization, Y Coulibaly   +48 more
core   +4 more sources