Results 181 to 190 of about 3,465,634 (408)

C4PS - Helping Facebookers Manage Their Privacy Settings

, 2012
Thomas Paul, Martin Stopczynski, Daniel Puscher, Melanie Volkamer, Thorsten Strufe   +4 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Effectiveness of a mobile application the emotion-focused training for helping professionals in reducing compassion fatigue and enhancing compassion satisfaction and resilience. [PDF]

Digit Health
Halamová J, Kanovský M, Blašková LJ.
europepmc   +1 more source

Helping Georgia? [PDF]

, 2002
Areshidze, Irakly G.
core   +1 more source

Helping People help themselves : Insights from behavioral economics for policies to counter addiction ( LIEPP Policy Brief, n°15)

, 2022
Jody L. Sindelar, Elizabeth Beasley
openalex   +1 more source

Serving time: how fine dining in jail is helping prisoners and satisfying customers [PDF]

, 2020
Alison McIntosh, Maria Gebbels, Tracy Harkison   +2 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Prosocial decisions in naturalistic helping scenarios are predicted by cost-benefit tradeoffs and individual disposition. [PDF]

Commun Psychol
Wu Q, Song M, Ayoub J, Dunning D, Tian D, Moradi-Pari E.   +5 more
europepmc   +1 more source

Study on a Resilient Helping Role Based on Top-down and Bottom-up Processing in Coordinated Behavior of a Triad

Jun Ichikawa, Kazushi Tsutsui, Keisuke Fujii   +2 more
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source