Results 241 to 250 of about 742,438 (343)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Youth Taskforce : progress report : summer 2009 [PDF]

, 2009

core  

Young Australian Women's Views on Peer Support for Self-Harm: A Qualitative Study. [PDF]

Int J Environ Res Public Health
Wang A, Rheinberger D, Tang S, Christensen H, Calear AL, Boydell K, Whitton A, Slade A, Hronis A.   +8 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prosociality is centred on intentions, not outcomes. [PDF]

Anim Cogn
Li L, Déniz T, Huff L, Jurkat S, Missana M, Tietz L, Grueneisen S.   +6 more
europepmc   +1 more source

Switching role from recipient to provider: How autonomy‐oriented help stimulates recipients' online helping behaviour [PDF]

Shuwen Li, Yaxin Lou, Wenan Hu, Zhifei Zhang   +3 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Provider influence on the home learning environment (EHLE) [PDF]

, 2011
Apps, Joanna, Hunt, Stephen, Klett-Davies, Martina, Page, Anne, Virgo, Susan   +4 more
core  

Large-scale community study reveals information sampling drives fairness decisions. [PDF]

Commun Psychol
Vahed S, Sanfey AG.
europepmc   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source