Results 251 to 260 of about 742,438 (343)

The Children's Fund: six case studies [PDF]

, 2005

core  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Preoperative Smoking Cessation in Chronic Respiratory Disease: A Community-Based Approach Guided by the Transtheoretical Model. [PDF]

Cureus
Mohajer-Bastami A, Moin S, Tweedlie L, Ahmed A, Agarwal A, Lala A, Gelber E, Whiteley G, Pouwels S, Khamise A, Khalid AW, Khalid A, Yang W, Patel B, Ahmad S.   +14 more
europepmc   +1 more source

Supplementary R code from Sex differences in helping effort reveal the effect of future reproduction on cooperative behaviour in birds.

, 2018
Philip A. Downing, Ashleigh S. Griffin, Charlie K. Cornwallis   +2 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Genomic Evidence for Local Adaptation to Elevation and Climate Sheds New Light on Variable Responses to Global Change in American Pikas (Ochotona princeps). [PDF]

Mol Ecol
Beever EA, Osterhoudt E, Linck EB.
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

The right age to fall in love. [PDF]

J Family Med Prim Care
Abhilasha P, Gautam N, Teenoth H, Bhardwaj S.   +3 more
europepmc   +1 more source

A helping hand: Applying behavioural science and co-design methodology to improve hand hygiene compliance in the hospital setting

Christiana Blair, Clare McCrudden, Alix Brazier, Sarah Huf, Alice M. Gregory, Fiona O’Driscoll, Tracey Galletly, Clare Leon-Villapalos, Helen Brown, Katherine Clay, Sheri L. Maxwell, Raymond Anakwe, Kate Grailey   +12 more
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source