This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding +13 more
wiley +1 more source
Application of a ddRT-PCR to quantify seasonal influenza virus for viral isolation
Viral isolation in cell cultures has been regarded for decades as the “gold standard” for the laboratory diagnosis of influenza viral infections. Not all viral strains could be isolated from clinical samples.
Yimeng Liu +11 more
doaj +1 more source
Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu +6 more
wiley +1 more source
Inhibitory effects of poly-galloyl-glucose series on virus-induced hemagglutination.
The data shown are the means ± standard deviations (SD) of two to three independent tests. The activity is expressed as the EC50 defined as the compound concentration producing 50% inhibition of hemagglutination induced by influenza virus, as estimated ...
Nan-Hao Chen (549500) +9 more
core +1 more source
Isolation of Two Strains of West Nile Virus during an Outbreak in Southern Russia, 1999
From July to September 1999, a widespread outbreak of meningoencephalitis associated with West Nile virus (Flavivirus, Flaviviridae) occurred in southern Russia, with hundreds of cases and dozens of deaths.
D.K. Lvov +15 more
doaj +1 more source
Evaluation of a Hemagglutination Test for Human Leptospirosis [PDF]
An indirect hemagglutination test for the diagnosis of leptospirosis is described; the test uses a soluble antigen from serotype patoc to sensitize sheep erythrocytes which are then fixed with glutaraldehyde. Evaluation of this procedure indicates that it is more reliable than the conventional macroscopic agglutination test and, in contrast with both ...
C R, Sulzer, W L, Jones
openaire +2 more sources
Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann +6 more
wiley +1 more source
Abstract Background The epidemiology of equine influenza (EI) in the United Kingdom has not been systematically described since the 2019 epidemic. Objectives To summarise UK EI surveillance (2020–2024), quantify outbreak seasonality and assess movement‐related sources. Study Design Retrospective observational analysis of national surveillance and horse
Fleur Whitlock +2 more
wiley +1 more source
Population screening for colorectal cancer means getting FIT:the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT) [PDF]
Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors?
Halloran, SP +7 more
core +1 more source
Isolation of Influenza Virus and Isolation of Influenza Virus and Typing in 1993
The aim of this project was to find out if influenza virus were involved in causing upper respiratory disease among susceptible people. One hundred and forty threat washings were collected from the patients living in Karaj, Tehran, and Mashhad during ...
Masoud Saboori, Mohammad Hasan Roostaie
doaj

