Results 41 to 50 of about 4,737 (170)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, Volume 20, Issue 2, Page 493-510, February 2026.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Computed Tomography and Magnetic Resonance Imaging Findings of a Malignant Hepatic Epithelioid Hemangioendothelioma

Journal of Investigative Medicine High Impact Case Reports, 2013
We report the case of a rare solitary small nodular form of malignant hepatic epithelioid hemangioendothelioma in a patient followed by computed tomography and gadoxetic acid (Gd-EOB-DTPA)–enhanced magnetic resonance imaging with histological analysis ...
Soo-heui Baek MD, Jung-Hee Yoon MD, PhD
doaj   +1 more source

Real‐World Experience of Efficacy and Tolerability of Continuous Infusion Ifosfamide for Advanced Soft Tissue and Bone Sarcoma Patients: A Single Centre Retrospective Cohort

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background In the absence of randomized trials, selecting second or later‐line therapies in advanced sarcoma generally hinges on histology, patient performance status, and toxicity profile. We herein report a real‐world sarcoma referral center experience on continuous infusion Ifosfamide (ciIFO), in advanced Soft tissue sarcomas (STS) and bone
Ilaria Mascagni, Alice Laffi, Maria Susanna Grimaudo, Ferdinando Carlo Maria Cananzi, Laura Samà, Salvatore Lorenzo Renne, Federico D’Orazio, Pierina Navarria, Elena Clerici, Carlo Carnaghi, Sara Farinatti, Erika Stucchi, Marialudovica Le Moli, Laura Giordano, Robert G. Maki, Armando Santoro, Alexia Francesca Bertuzzi   +16 more
wiley   +1 more source

TFE3 rearranged epithelioid hemangioendothelioma of the lymph node: A rare primary presentation of vascular tumor

Indian Journal of Pathology and Microbiology
Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular tumor that has been described in numerous sites such as soft tissue, liver, and lungs. However, primary lymph nodal presentation of hemangioendothelioma is extremely rare.
Ann Thomas, Swapnil U. Rane, Santosh Menon   +2 more
doaj   +1 more source

Spontaneous Bilateral Hemothorax as a Case of Epithelioid Hemangioendothelioma (EHE)

Case Reports in Oncological Medicine, 2019
Epithelioid hemangioendothelioma (EHE) is a rare tumor that is vascular in origin, arising from the endothelial or preendothelial cells. It can occur at different sites of the body, commonly in the liver, lungs, and bone.
Essa M. AlGhunaim, Hafsa AlNajem, Derar S. AlShehab   +2 more
doaj   +1 more source

Pleuropulmonary Epithelioid Hemangioendothelioma

Cureus
We present the CT, thoracoscopic, and histological findings of a 55-year-old female with pleuropulmonary epithelioid hemangioendothelioma. The CT scan revealed pleuropulmonary lesions, and thoracoscopy allowed direct visualization and biopsy of the lesions.
Haroun, Philippe, Salame, Hanna, Tack, Denis, Dehon, Romain   +3 more
openaire   +2 more sources

ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju, Tao Zhang, Jianchen Cui, Yulim Lee, Suho Lee, Ho Min Kim, Boohwi Hong, Jiho Park, Chul Hee Choi, Hyon‐Seung Yi, Jun Young Heo, Woosuk Chung   +11 more
wiley   +1 more source

Living-related liver transplant to treat epithelioid hemangioendothelioma – a case report

Brazilian Journal of Transplantation, 2005
Introduction: Epithelioid hemangioendothelioma of liver is a rare, low-grade neoplasm of vascular origin that has an unpredictable malignant potential. It preferentially arises in soft tissues and bones, and seldom in the liver.
Marcelo A. F. Ribeiro Jr, Christian Evangelista Garcia, Telma Eugênio dos Santos, Adavio de Oliveira e Silva , Regina Leitão , Cristiane Maria de Freitas Ribeiro, Alexandre Zanchenko Fonseca, Camila de Grande Cambiaghi, Paulo Roberto de Arruda Zantut, Luiz Augusto Carneiro D’Albuquerque   +9 more
doaj   +1 more source

Tibial epithelioid hemangioendothelioma

Human Pathology: Case Reports, 2020
Epithelioid hemangioendotheliomas (EHE) represent less than 1% of all bone tumors. They often present in the long tubular bones or in the axial skeleton, but are often multifocal in nature and can present in the liver and lung. This paper presents a case
Eugene Kim, Ronald Williams, Amanda Rivera-Begeman   +2 more
doaj   +1 more source

Single‐nucleus RNA sequencing reveals the distinct heterogeneity of primary pulmonary sarcomas (PPS) and pulmonary sarcomatoid carcinoma (PSC)

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Single‐nucleus RNA sequencing (snRNA‐seq) maps the cellular diversity of pulmonary sarcomatoid carcinoma (PSC) and primary pulmonary sarcomas (PPS). AT2 cells, a major source of epithelial cells in PSC, underwent malignant transformation primarily through epithelial–mesenchymal transition, suggesting AT2 cells may serve as the origin of PSC.
Jianfei Zhu, Yanlu Xiong, Shouzheng Ma, Jun Wei, Jiakuan Chen, Wenchen Wang, Qianqian Duan, Qin Zhang, Dongsheng Chen, Wanglong Deng, Tao Jiang, Jie Lei   +11 more
wiley   +1 more source