Results 51 to 60 of about 12,136 (174)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, Volume 20, Issue 2, Page 493-510, February 2026.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Real‐World Experience of Efficacy and Tolerability of Continuous Infusion Ifosfamide for Advanced Soft Tissue and Bone Sarcoma Patients: A Single Centre Retrospective Cohort

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background In the absence of randomized trials, selecting second or later‐line therapies in advanced sarcoma generally hinges on histology, patient performance status, and toxicity profile. We herein report a real‐world sarcoma referral center experience on continuous infusion Ifosfamide (ciIFO), in advanced Soft tissue sarcomas (STS) and bone
Ilaria Mascagni, Alice Laffi, Maria Susanna Grimaudo, Ferdinando Carlo Maria Cananzi, Laura Samà, Salvatore Lorenzo Renne, Federico D’Orazio, Pierina Navarria, Elena Clerici, Carlo Carnaghi, Sara Farinatti, Erika Stucchi, Marialudovica Le Moli, Laura Giordano, Robert G. Maki, Armando Santoro, Alexia Francesca Bertuzzi   +16 more
wiley   +1 more source

Hepatic epithelioid hemangioendothelioma: A clinocopathological correlation

Indian Journal of Pathology and Microbiology, 2022
Primary hepatic epithelioid hemangioendothelioma (HEHE) is a rare tumor with an incidence of
Apurva Dale Mundada, Kedar Deodhar, Mukta Ramadwar, Munita Bal, Rajiv Kumar   +4 more
doaj   +1 more source

ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju, Tao Zhang, Jianchen Cui, Yulim Lee, Suho Lee, Ho Min Kim, Boohwi Hong, Jiho Park, Chul Hee Choi, Hyon‐Seung Yi, Jun Young Heo, Woosuk Chung   +11 more
wiley   +1 more source

Hemangioendotelioma do lábio.

Acta Médica Portuguesa, 1994
Hemangioendothelioma is a relatively uncommon tumor of the oral cavity. This article reviews the literature on hemangioendothelioma and presents one additional case of this neoplasm found on the lip.
L G Brentegani, L C Pardini, L A Salata, A L Rosa   +3 more
doaj   +1 more source

Single‐nucleus RNA sequencing reveals the distinct heterogeneity of primary pulmonary sarcomas (PPS) and pulmonary sarcomatoid carcinoma (PSC)

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Single‐nucleus RNA sequencing (snRNA‐seq) maps the cellular diversity of pulmonary sarcomatoid carcinoma (PSC) and primary pulmonary sarcomas (PPS). AT2 cells, a major source of epithelial cells in PSC, underwent malignant transformation primarily through epithelial–mesenchymal transition, suggesting AT2 cells may serve as the origin of PSC.
Jianfei Zhu, Yanlu Xiong, Shouzheng Ma, Jun Wei, Jiakuan Chen, Wenchen Wang, Qianqian Duan, Qin Zhang, Dongsheng Chen, Wanglong Deng, Tao Jiang, Jie Lei   +11 more
wiley   +1 more source

Comparative Analysis of a Dual DNA–RNA Panel and a DNA‐Only Panel for Sarcoma: Real‐World Data From a Nationwide Genomic Database

Cancer Science, Volume 117, Issue 1, Page 156-168, January 2026.
Dual DNA–RNA panel with matched tumor–normal testing may improve diagnostic accuracy and inform treatment decisions in the routine clinical management of sarcoma. ABSTRACT Next‐generation sequencing‐based comprehensive cancer genomic profiling is promising in cancer management; however, most studies rely on tumor‐only DNA panels from single ...
Eiji Nakata, Kiichiro Ninomiya, Tatsunori Osone, Daisuke Ennishi, Shuta Tomida, Tomohiro Fujiwara, Toshiyuki Kunisada, Mashu Futagawa, Akira Hirasawa, Shinichi Toyooka, Toshifumi Ozaki   +10 more
wiley   +1 more source

Primary Cardiac Hemangioendothelioma in an Infant: A Case Report

Clinical Pediatric Hematology-Oncology, 2019
Primary cardiac tumors are rare, with a prevalence of 0.001-0.2%. Among such tumors, cardiac hemangioendotheliomas are some of the most uncommon. In Korea, there have been no reports of hemangioendothelioma occurring in the heart of infants.
Jeong-wook Seo, Mi Kyoung Song, Sung-hye Park, Hye Eun Park, Sin Ae Park   +4 more
doaj   +1 more source

Multifocal Pseudomyogenic Hemangioendothelioma Involving the Scalp and Nose, Misdiagnosed as A Sarcoma: A Rare Case Report

Türk Patoloji Dergisi, 2022
This case report aims to present clinicopathological features of an extremely rare case of multifocal pseudomyogenic hemangioendothelioma (PMHE) in the scalp.
Neha MITTAL, Bharat REKHI, Priyamvada SINGHAL, Munita BAL, Swapnil RANE, Asawari PATIL, Shivakumar THIAGARAJAN   +6 more
doaj   +1 more source

Bleomycin electrosclerotherapy for kaposiform hemangioendothelioma with Kasabach–Merritt phenomenon in an adult

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Jakob Veeser, Raphael Wilhelm, Janina Dietzel, Yalda Ghoreishi, Nora Laubach, Nora Elspaß, Maike Kaufhold, Beate Weidenthaler‐Barth, Christian Rose, Stephan Grabbe, Henner Stege, Hadrian Nassabi   +11 more
wiley   +1 more source