Results 41 to 50 of about 5,310 (197)

Integration of Efanesoctocog Alfa in Clinical Practice for Children, Adolescents, and Young Adults With Severe Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Efanesoctocog alfa is a novel, “ultra‐extended half‐life” FVIII concentrate for bleed treatment and prevention in haemophilia A. Clinical trials excluded individuals with active or prior FVIII inhibitors, those on emicizumab, and previously untreated patients (PUPs).
Debbie Jiang, Natalie Johnston, Daniel Echelman, Stacy E. Croteau   +3 more
wiley   +1 more source

Low‐Load Quadriceps Strengthening With Blood Flow Restriction in Adults With Haemophilic Knee Arthropathy: A Randomised Controlled Trial

Haemophilia, EarlyView.
Abstract Introduction Haemophilic knee arthropathy leads to a reduction in muscle mass and strength. Blood flow restriction (BFR) involves the application of a compressive cuff that enables strength training with reduced loads. Objective To evaluate safety as the primary outcome and the efficacy (muscle strength and activation, functional capacity and ...
Mar Villalón‐González, Raúl Pérez‐Llanes, José Antonio López‐Pina, Rubén Cuesta‐Barriuso, Elena Donoso‐Úbeda   +4 more
wiley   +1 more source

Optimal management of hemophilic arthropathy and hematomas

Journal of Blood Medicine, 2014
Sébastien Lobet,1,2 Cedric Hermans,1 Catherine Lambert1 1Hemostasis-Thrombosis Unit, Division of Hematology, 2Division of Physical Medicine and Rehabilitation, Cliniques Universitaires Saint-Luc, Brussels, Belgium Abstract: Hemophilia is a ...
Lobet S, Hermans C, Lambert C
doaj  

A pathological joint–liver axis mediated by matrikine-activated CD4+ T cells

Signal Transduction and Targeted Therapy
The knee joint has long been considered a closed system. The pathological effects of joint diseases on distant organs have not been investigated.
Junzhi Yi, Hui Zhang, Fangyuan Bao, Zhichu Chen, Yuliang Zhong, Tianning Ye, Xuri Chen, Jingyi Qian, Mengya Tian, Min Zhu, Zhi Peng, Zongyou Pan, Jianyou Li, Zihao Hu, Weiliang Shen, Jiaqi Xu, Xianzhu Zhang, Youzhi Cai, Mengjie Wu, Hua Liu, Jing Zhou, Hongwei Ouyang   +21 more
doaj   +1 more source

Glanzmann Thrombasthenia Associated with Siderotic Synovitis and Arthropathy: A Case Report

Journal of Blood Medicine, 2023
Mouhammad J Alawad,1 Mohammad Abu-Tineh,2 Awni Alshurafa,2 Alaa Al-Taie,3 Anil Yousaf,2 Mohamed A Yassin2 1Department of Medical Education, Internal Medicine Residency Program, Hamad Medical Corporation, Doha, Qatar; 2Department of Medical Oncology ...
Alawad MJ, Abu-Tineh M, Alshurafa A, Al-Taie A, Yousaf A, Yassin MA   +5 more
doaj  

Magnitude of arthropathy in patients with hemophilia: A single-center experience

Iraqi Journal of Hematology, 2017
Background: Hemophilia is a sex-linked bleeding disorder. Affected patients suffer spontaneous or post-traumatic bleeding into various sites of the body, mainly into joints, depending on the level of coagulation factor deficiency.
Rawand Polus Shamoon
doaj   +1 more source

Posttraumatic hemarthrosis in view of the inflammation theory

Гений oртопедии, 2023
Introduction Post-traumatic hemarthrosis is identified as intra-articular hemorrhage accompanied by five classic signs of inflammation: hyperemia, hyperthermia, edema, pain and changes in the joint function.
Olga V. Berdiugina, Valery A. Chereshnev, Kirill A. Berdiugin   +2 more
doaj   +1 more source

Rebalancing Hemostasis: Fitusiran as a First‐in‐Class RNAi Therapy in Hemophilia A and B

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Fitusiran is a first‐in‐class RNA interference (RNAi) therapy that lowers antithrombin (AT) to rebalance hemostasis in people with Hemophilia A or B, with or without inhibitors. Its recent FDA approval marks a major shift toward factor‐independent prophylaxis.
Raza Ur Rehman, Rida Fatima, Aymar Akilimali   +2 more
wiley   +1 more source

Exploration of the minimum necessary FVIII level at different physical activity levels in pediatric patients with hemophilia A

Frontiers in Pediatrics, 2022
BackgroundPhysical activity can increase joint stability and reduce the risk of injury in hemophilia patients. There is limited clinical data on target trough FVIII levels during physical activity in hemophilia A patients.
Di Ai, Kun Huang, Gang Li, Yingzi Zhen, Xinyi Wu, Ningning Zhang, Aihua Huo, Zhenping Chen, Runhui Wu   +8 more
doaj   +1 more source

Podium Presentation Title: Tranexamic Acid has no Effect on Postoperative Hemarthrosis or Pain After Tibial Tubercle Osteotomy [PDF]

, 2023
Michael J. Alaia, Jordan W. Fried, Eoghan T. Hurley, Andrew S. Bi, Kirk A. Campbell, Eric J. Strauss, Laith M. Jazrawi, Michael J. Alaia   +7 more
openalex   +1 more source