Results 51 to 60 of about 5,310 (197)

Balancing Promise and Peril: Hemophilia Gene Therapy Insights

IUBMB Life, Volume 78, Issue 1, January 2026.
ABSTRACT Hemophilia is an inherited disorder characterized by impaired blood clotting caused by mutations in the genes responsible for producing coagulation factor (F) VIII (hemophilia A, HA) or FIX (hemophilia B, HB). Current treatment primarily relies on replacement therapy, involving frequent and costly infusions of FVIII or FIX concentrates.
Saicharan Akula, Ester Borroni, Alessia Cottonaro, Antonia Follenzi, Simone Merlin   +4 more
wiley   +1 more source

Current Uses for Medical Imaging With Orthopaedic Implant Technology

Journal of Orthopaedic Research, Volume 44, Issue 1, January 2026.
ABSTRACT Musculoskeletal applications have been at the forefront of medical imaging since the first‐ever x‐ray was taken of a hand. Radiography remains routine in orthopaedics for surgical planning and diagnosing implant complications. Fluoroscopy is used to guide intra‐operative implant placement and to assess kinematics of different implants ...
Jordan S. Broberg, Matthew G. Teeter
wiley   +1 more source

Acquired Factor VIII Inhibitors: Three Cases

Turkish Journal of Hematology, 2013
Acquired hemophilia A is a rare, but devastating bleeding disorder caused by spontaneous development of autoantibodies directed against coagulation factor VIII.
Tay Za Kyaw, S. Jayaranee, Ping Chong Bee, Edmund Fui Min Chin   +3 more
doaj   +1 more source

Hydrogel Microspheres for Biomedical Applications

Small Science, Volume 6, Issue 1, January 2026.
Hydrogel microspheres (HMs) play pivotal roles in biomedical applications, such as drug delivery, cell culture, regenerative medicine, wound healing, and tumor immunity. This review focuses on the latest findings to provide a more comprehensive understanding of HMs for biomedical applications.
Yingkang Huang, Xi Zhu, Jinhong Zhou, Henan Li, Wei Zhang, Danyang Shen, Ziyan Huang, Tianbo Zhang, Lin Zhuang, Lei Qin, Xiaofeng Xue, Yunjie Lu   +11 more
wiley   +1 more source

Addition of a 2‐Limb Lateral Extra‐articular Procedure to Anterior Cruciate Ligament Reconstruction Does Not Increase Early Complications in Pediatric Patients at Minimum 1‐Year Follow‐Up

Arthroscopy, Sports Medicine, and Rehabilitation, Volume 7, Issue 6, December 2025.
Purpose To compare the rates and types of early complications in pediatric patients undergoing a 2‐limb lateral extra‐articular procedure (LEAP) alongside anterior cruciate ligament reconstruction (ACLR) versus ACLR alone. Methods The records of patients who underwent primary ACLR at a single tertiary children’s hospital were reviewed for this ...
Samuel I. Rosenberg, Elizabeth H. Merritt, Neeraj M. Patel   +2 more
wiley   +1 more source

CLINICAL PROFILE OF PATIENTS WITH RARE INHERITED COAGULATION DISORDERS: A RETROSPECTIVE ANALYSIS OF 67 PATIENTS FROM NORTHERN INDIA

Mediterranean Journal of Hematology and Infectious Diseases, 2012
<p><strong>Introduction</strong>: Inherited bleeding disorders are characterized by the absence or reduced level of clotting factors, and the clinical manifestations vary according to the type and magnitude of the deficient factor.
Sanjeev Kumar Sharma, Suman Kumar, Tulika Seth, Pravas Mishra, Narendra Agrawal, Gurmeet Singh, Avinash Singh, Manoranjan Mahapatra, Seema Tyagi, Haraprasad Pati, Renu Saxena   +10 more
doaj   +3 more sources

Arthroscopic Targeted Screw Placement: A Minimally Invasive Approach for Hindfoot Fractures

Arthroscopy Techniques, Volume 14, Issue 12, December 2025.
Abstract Arthroscopic techniques have emerged as a promising alternative to traditional open reduction internal fixation in the treatment of foot and ankle fractures, offering minimally invasive methods to address intra‐articular fractures. These techniques provide direct visualization of the fracture site while preserving the soft tissue envelope and ...
Srihan Anand, Kevin D. Martin
wiley   +1 more source

Hemarthrosis associated with sodium warfarin therapy [PDF]

Arthritis & Rheumatism, 1976
AbstractThree patients with hemarthrosis of the knee joint complicating sodium warfarin oral anticoagulation therapy are described. In all 3 the prothrombin time was at least 2.4 times the control value at the time of hemarthrosis. After initial bleeding was controlled, 2 patients had recurrences at times when their prothrombin times were again more ...
J H, Wild, N J, Zvaifler
openaire   +2 more sources

Evaluation of the Viscoelastic Properties of Lower-Extremity Muscles of Pediatric Hemophilia Patients Using Myotonometric Measurements

Children
This study aimed to evaluate the viscoelastic properties of lower-extremity muscles in pediatric hemophilia (FVIII-IX) patients. The study included 20 severe- and moderate-type right-dominant hemophilia patients diagnosed with hemophilia A–B and 20 ...
Tuğba Gönen, Serkan Usgu, Yavuz Yakut, Sinan Akbayram   +3 more
doaj   +1 more source

Stridor Misleading as Asthma: Unveiling Case of Shabbir Syndrome in an Atopy‐Prone 2.5 Years Old Pakistani

Respirology Case Reports, Volume 13, Issue 11, November 2025.
Laryngo‐onycho‐cutaneous syndrome (LOCS), or Shabbir's syndrome, linked to mutations in the LAMA3 gene, is predominantly observed in children from Punjabi families. We present the case of a 2.5‐year‐old male with LOCS who was initially misdiagnosed with asthma due to progressive hoarseness and stridor.
Nabeel Ahmad, Ali Gohar, Abdul Rehman Shahid Khan, Armaghan Hanif, Rohail Sani, Khizra Saeed, Masab Ali, Muhammad Husnain Ahmad, Fida Hussain   +8 more
wiley   +1 more source