Results 61 to 70 of about 5,913 (233)

Acquired Factor VIII Inhibitors: Three Cases

Turkish Journal of Hematology, 2013
Acquired hemophilia A is a rare, but devastating bleeding disorder caused by spontaneous development of autoantibodies directed against coagulation factor VIII.
Tay Za Kyaw, S. Jayaranee, Ping Chong Bee, Edmund Fui Min Chin   +3 more
doaj   +1 more source

Image‐based robotic total knee arthroplasty preserves the knee joint line level even in advanced fixed flexion deformities when combined with functional alignment principles: A retrospective comparative cohort study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Fixed flexion deformity (FFD) is traditionally addressed in total knee arthroplasty (TKA) with extensive soft tissue release and distal femoral recut, which increases bone stock consumption and raises the knee joint line (JL). This study aimed to evaluate differences in the anatomical restoration of the JL and bone stock preservation ...
Giacomo Pacchiarotti, Alessandro Todesca, George Mihai Avram, Giovanni Longo, Domenico Paolicelli, Stefano Gumina   +5 more
wiley   +1 more source

Exploration of the minimum necessary FVIII level at different physical activity levels in pediatric patients with hemophilia A

Frontiers in Pediatrics, 2022
BackgroundPhysical activity can increase joint stability and reduce the risk of injury in hemophilia patients. There is limited clinical data on target trough FVIII levels during physical activity in hemophilia A patients.
Di Ai, Kun Huang, Gang Li, Yingzi Zhen, Xinyi Wu, Ningning Zhang, Aihua Huo, Zhenping Chen, Runhui Wu   +8 more
doaj   +1 more source

Physical Activity Awareness and Understanding of Treatment Protection Among People With Haemophilia and Their Caregivers in Central Europe

Haemophilia, EarlyView.
ABSTRACT Background Physical activity is now considered generally beneficial for persons with haemophilia (PWH). However, the specific type and extent of activity and its impact on quality of life (QoL) and bleed protection during exercise is under‐researched.
Angelika Batorova, Atanas Banchev, Ana Boban, Brigitte Brand, Melen Brinza, Barbara Faganel Kotnik, Csongor Kiss, Gediminas Puras, Jan Rajnoch, Ester Zapotocka   +9 more
wiley   +1 more source

Profiling of Anti‐FVIII Antibodies in Acquired Haemophilia A: ‘Insights into Domain Specificity, Isotype Variability, and Clinical Correlations’

Haemophilia, EarlyView.
ABSTRACT Introduction Acquired haemophilia A (AHA) is a rare autoimmune disorder caused by autoantibodies against coagulation factor VIII (FVIII), resulting in significant bleeding risks. Aim To characterize the anti‐FVIII antibody profile in AHA patients by assessing isotypes, subclasses, and correlations with key clinical parameters.
Ann‐Cristin Berkemeier, Isabell Matuschek, Katrin Hartlieb, Thilo Albert, Natascha Marquardt, Johannes Oldenburg, Behnaz Pezeshkpoor   +6 more
wiley   +1 more source

PRP or not PRP: Is the debate surrounding platelets‐based blood‐derived products evolving?

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 33, Issue 5, Page 1920-1924, May 2025.
Abstract The increasing interest in biologic treatments for musculoskeletal disorders has led to the advancement of orthobiologics, particularly in non‐operative care through injectable therapies. However, defining these treatments clearly is crucial for proper clinical application.
Enrico Ragni, Michela Maria Taiana, Tomislav Čengić, Laura de Girolamo, Marko Ostojić   +4 more
wiley   +1 more source

CLINICAL PROFILE OF PATIENTS WITH RARE INHERITED COAGULATION DISORDERS: A RETROSPECTIVE ANALYSIS OF 67 PATIENTS FROM NORTHERN INDIA

Mediterranean Journal of Hematology and Infectious Diseases, 2012
<p><strong>Introduction</strong>: Inherited bleeding disorders are characterized by the absence or reduced level of clotting factors, and the clinical manifestations vary according to the type and magnitude of the deficient factor.
Sanjeev Kumar Sharma, Suman Kumar, Tulika Seth, Pravas Mishra, Narendra Agrawal, Gurmeet Singh, Avinash Singh, Manoranjan Mahapatra, Seema Tyagi, Haraprasad Pati, Renu Saxena   +10 more
doaj   +3 more sources

Posttraumatic hemarthrosis in view of the inflammation theory

Гений oртопедии, 2023
Introduction Post-traumatic hemarthrosis is identified as intra-articular hemorrhage accompanied by five classic signs of inflammation: hyperemia, hyperthermia, edema, pain and changes in the joint function.
Olga V. Berdiugina, Valery A. Chereshnev, Kirill A. Berdiugin   +2 more
doaj   +1 more source

Management challenge of a rare concomitant platelet glycoprotein IV/CD36 and IIb/IIIa deficiencies: Case illustration

Transfusion, Volume 65, Issue 4, Page 767-772, April 2025.
Abstract Introduction/Background Platelet membrane glycoproteins (GPs) serve several functions, the most significant of which is their role in primary hemostasis. Among these, GP IIb/IIIa is the primary fibrinogen receptor and is essential for platelet aggregation.
Tro Sekayan, Elizabeth S. Allen, Patricia Kopko, Laura D. Stephens, Mitchell Zhao, Brian R. Curtis, Mia J. Sullivan, Valerie Trapp‐Stamborski, Annette von Drygalski   +8 more
wiley   +1 more source

Mild or moderate hemophilia is not always a mild or moderate bleeding disorder: Back to the clinical phenotype

HemaSphere, Volume 9, Issue 3, March 2025.
Abstract In a previous paper, a comprehensive clinicopathologic approach to mild and moderate bleeding disorders (MBD) was proposed by an international working group (IWG) as a part of a project promoted by the European Hematology Association (EHA) on the development of guidelines on the various MBDs.
Francesco Rodeghiero, Lisanna Ghiotto, Luca Pontalto, Alessandro Casini, Giancarlo Castaman, Rezan Abdul‐Kadir, Erik Berntorp, Imre Bodó, Manon Degenaar‐Dujardin, Karin Fijnvandraat, Paolo Gresele, Nigel S. Key, Riitta Lassila, Frank W. G. Leebeek, David Lillicrap, Mike Makris, Stephan Meijer, Diego Mezzano, Patrizia Noris, Ingrid Pabinger, Margaret V. Ragni, David Silva, Alok Srivastava, Alberto Tosetto, Jerzy Windyga, Barbara Zieger   +25 more
wiley   +1 more source